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A tlanta Biologicals is a premier global supplier of high quality life science research products.
We specialize in the development and production of a full line of cell culture sera, serum alterna-tives, cell culture media, custom media products, cell culture reagents, media supplements, cell separation media, and cytokines.
A high quality FBS product at exceptional value. Especially suited where special com-
ponent testing, such as the hormone assay, is not required. It is suitable for many
cell culture applications, and is comprehensively tested for performance and quality
assurance. Lots are manufactured from US or USDA-approved origin material follow-
ing stringent manufacturing and quality control procedures.
A high quality FBS product that is most widely used among cell culture researchers.
An extensive biochemical proﬁ le is provided in addition to comprehensive quality
assurance testing. It is priced lower than FBS-Premium Select and FBS-Optima, and
demonstrates superior performance with a broad spectrum of cell types. Lots are
manufactured from USDA-approved origin material following stringent manufacturing
This high quality FBS product meets the requirements of most cell lines and is suit-
able for general applications. An extensive biochemical proﬁ le and an extended virus
test panel are provided in addition to comprehensive quality assurance testing. Each
lot is manufactured exclusively from US origin material following stringent manufac-
turing and quality control procedures.
The highest grade FBS available, suitable for the most demanding and sensitive
cell lines. It is also widely used when a hormone proﬁ le, an extensive biochemical
proﬁ le and/or an extended virus test panel is required, in addition to comprehen-
sive quality assurance testing. Lots are manufactured from US or USDA-approved
origin material following stringent manufacturing and quality control procedures.
Specialty Fetal Bovine Sera available from Atlanta Biologicals:
Embryonic Stem Cell Qualified Fetal Bovine SerumFor applications utilizing embryonic stem (ES) cells, the success of the research is highly dependent on identifying
a suitable lot of FBS. With Atlanta Biologicals’ ES Qualiﬁ ed Fetal Bovine Serum, time consuming pre-screening of
multiple serum lots is no longer required. We test our highest quality FBS lots for particular suitability for cultur-
ing embryonic stem cells. The screening includes plating efﬁ ciency, colony morphology and cytotoxicity assays.
Selected lots must offer outstanding performance with embryonic stem cells while maintaining the cells in their
Hybridoma Qualified Fetal Bovine SerumThis serum is ideally suited for culturing hybridoma and myeloma cells. High quality Fetal Bovine Serum is
screened to identify lots that offer optimal performance with these cells. Hybridoma Qualiﬁ ed lots must show
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Insect Cell Qualified Fetal Bovine SerumHigh quality FBS is tested for optimal performance with insect cells. Lots that demonstrate superior cell yield,
exceptional viability and lack of cytotoxity in cell culture systems using insect cells are selected as Insect Cell
TET Tested Fetal Bovine SerumThe Tet systems are the most widely applied inducible gene expression systems. In each system, a tetracycline-
controlled transactivator interacts with a responsive promoter to regulate expression of the gene of interest.
Expression is controlled from outside by the effector substances tetracycline or one of its derivatives. The pres-
ence of tetracycline or its derivatives in serum may interfere with these tetracycline-regulated gene expression
systems. TET Tested Fetal Bovine Serum is speciﬁ cally designed for use in Tet systems and cell lines. The tetracy-
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Charcoal/Dextran Fetal Bovine SerumPre-selected high quality FBS is processed using a proprietary Charcoal/Dextran treatment proven to reduce the
levels of many hormones, steroids and growth factors. Each lot produced is tested for various hormones and ste-
roids before and after treatment to conﬁ rm the efﬁ cacy of the process. Charcoal/Dextran treated FBS is used in
applications requiring lower levels of hormones, steroids or growth factors in serum, such as insulin and estrogen
Dialyzed FBS is used in cell culture systems requiring a more deﬁ ned environment of small molecules. Dialysis
reduces the concentration of low molecular weight components such as nucleotides, amino acids, hormones,
salts and various small proteins. Two different Dialyzed FBS products are available. The serum is dialyzed against
physiological saline using either a 10,000 Dalton or a 12,000 to 14,000 Dalton cutoff membrane. The process is
controlled by precisely monitoring the glucose concentration throughout the procedure. Exhaustive dialysis is not
performed in order to prevent precipitation and inactivation of serum peptides.
Gamma Irradiated Fetal Bovine SerumGamma Irradiation is recognized as an effective method of inactivating viruses and other adventitious agents in se-
rum. Even though FBS is stringently tested, low levels of common bovine viruses below the detection limits of cur-
rent test methods may exist. Gamma Irradiated FBS is exposed to a 60Co source at a delivered dose of 25-35 kGy.
Exposure of FBS to this dosage has been shown to remove up to 6 logs of many extraneous agents while preserving
the growth performance characteristics of serum.
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