Opening [Standard presentation] A look back at our past Jean-Louis Vincent (Brussels , Belgium) Report of the Round Table conference on “Evidence in the ICU” John J Marini (St Paul , United States) - Djillali Annane (Garches , France) EGDT ProCESS? Derek C Angus (Pittsburgh , United States) Immunotherapy of Sepsis - the New Frontier Richard Hotchkiss (St Louis , United States) Big data [Standard presentation] Data mining with MIMIC Leo Anthony Celi (Cambridge, United States) Merging genetic with clinical data Jean-Paul Mira (Paris , France) eRecords for benchmarking and performance assessment Theodore J Iwashyna (Ann Arbor, United States) eResearch: Why it's not just fancy chart review John Kellum (Pittsburgh , United States) Big international consortia John C Marshall (Toronto , Canada) The experience of the Surviving Sepsis Campaign Mitchell Levy (Providence , United States) Government use of electronic data Jeremy M Kahn (Pittsburgh , United States) Understanding sepsis [Standard presentation] Interactions between bacteria and other pathogens Philippe Montravers (Paris , France) Receptor signaling in the pathogenesis of sepsis Tom van der Poll (Amsterdam , Netherlands) Mechanisms of cell death in sepsis Richard Hotchkiss (St Louis , United States) Apoptosis John C Marshall (Toronto , Canada) Autophagy Greet Van Den Berghe (Leuven , Belgium) Stressful encounters Mervyn Singer (London , United Kingdom) Role of the inflammasome Thierry Calandra (Lausanne , Switzerland) Immunoparalysis Peter Pickkers (Nijmegen , Netherlands) Neurophysiologic bases [Standard presentation] Cerebral metabolism Mauro Oddo (Lausanne , Switzerland) Intracerebral mechanics Marek Mirski (Baltimore , United States) Cerebral perfusion Giuseppe Citerio (Monza , Italy) Electrical activity of the brain Marek Mirski (Baltimore , United States) Regional circulation [Standard presentation] In the brain Nino Stocchetti (Milan , Italy) In the lung Paolo Pelosi (Genoa , Italy) In the kidney Rinaldo Bellomo (Melbourne, Australia) In the GI tract Jukka Takala (Bern , Switzerland) In the muscle and skin Jan Bakker (Rotterdam , Netherlands) Respiratory failure: Pathophysiological aspects [Standard presentation] Control of breathing during mechanical ventilation Dimitris Georgopoulos (Heraklion , Greece) How I distinguish hydrostatic and increased permeability pulmonary edema Jean-Louis Teboul (Le Kremlin-Bicêtre , France) Gas exchange in ARDS Antonio Pesenti (Milan , Italy) Peripheral airways and hyperinflation Christian Karagiannidis (Köln, Germany) Mechanical interdependence of the chest wall and abdomen John J Marini (St Paul , United States) The kidney in respiratory failure Michael Darmon (Saint-Priest-en-Jarez, France) Fluid in the wrong place [Standard presentation] Role of the glycocalyx Can Ince (Amsterdam , Netherlands) Managing by echo Paul H Mayo (New York , United States) Pleural effusion and chest wall behavior Luciano Gattinoni (Milan , Italy) Tap it or ignore it? John J Marini (St Paul , United States) What to do with ascites? Pere Ginès (Barcelona, Spain) Have me made progress? [Standard presentation] In sepsis Rinaldo Bellomo (Melbourne, Australia) In renal failure Giovanni Landoni (Milan, Italy) In pediatric critical care Niranjan (Tex) Kissoon (Vancouver , Canada) In ARDS Arthur S Slutsky (Toronto , Canada) Beta-blockade for everyone? [Standard presentation] In the perioperative patient Stefan De Hert (Ghent , Belgium) In the cirrhotic patient Thomas Sersté (Bruxelles, Belgium) In the neurosurgical patient Peter Le Roux (Wynnewood, United States) In the cardiovascular patient Antonio Messias (Loures, Portugal) In the septic patient Bruno Levy (Vandoeuvre Les Nancy , France) Clinical studies in septic shock Andrea Morelli (Rome , Italy) Empiric antimicrobial therapy [Standard presentation] Empiric therapy Marin Kollef (St Louis , United States) Mono- or biotherapy Thierry Calandra (Lausanne , Switzerland) Therapy of severe CAP Michael S Niederman (Mineola , United States) The special case of pneumococcal CAP Jean-Paul Mira (Paris , France) Therapy of VAP Richard Wunderink (Chicago , United States) Should patients with septic shock be treated empirically with antifungals? Markus Ruhnke (Berlin , Germany) Target blood pressure [Standard presentation] MAP: The higher the better in septic shock? Claude Martin (Marseille , France) How to run the circulation at the lowest possible pressures Jan Bakker (Rotterdam , Netherlands) Consider the MAP gap Rinaldo Bellomo (Melbourne, Australia) Does one blood pressure target fit all? Peter Radermacher (Ulm , Germany) Optimal pressure for the body's organs Michael Pinsky (Pittsburgh , United States) Renal failure in cirrhosis: Vasopressin or norepinephrine? Paolo Angeli (Padova , Italy) A pragmatic approach to optimize blood pressure Stephen Trzeciak (Camden , United States) Another look a vasopressors [Standard presentation] Myocardial effects of vasopressors Bruno Levy (Vandoeuvre Les Nancy , France) Hemodynamic effects of norepinephrine revisited Xavier Monnet (Le Kremlin-Bicêtre , France) Anything new about vasopressin? Daniel De Backer (Brussels , Belgium) A place for angiotensin II? Lakhmir Chawla (Washington , United States) Blood lactate in 2014 [Standard presentation] A review of its metabolism in shock states Bruno Levy (Vandoeuvre Les Nancy , France) Lactate has a beneficial role Antonio Pesenti (Milan , Italy) Time course of lactate in hemorrhagic shock Paul E Pepe (Dallas , United States) Time course of lactate in septic shock Jan Bakker (Rotterdam , Netherlands) Blood lactate as a resuscitation target Gernot Marx (Aachen , Germany) Intraabdominal hypertension [Standard presentation] How to measure and improve abdominal wall compliance Manu Malbrain (Antwerp , Belgium) Prevention is the key Jan De Waele (Ghent , Belgium) Higher tidal volume and lower PEEP? Paolo Pelosi (Genoa , Italy) Higher PEEP and lower tidal volume? Arthur S Slutsky (Toronto , Canada) Adjunct therapies in sepsis [Standard presentation] Should fever be treated? Paul Young (Wellington, New Zealand) Immunoglobulins Axel Nierhaus (Hamburg , Germany) IgM with IgG? Figen Esen (Istanbul , Turkey) Statins Laurent Papazian (Marseille , France) Beta-blockade Djillali Annane (Garches , France) Levosimendan is my favorite drug Andrea Morelli (Rome , Italy) Antithrombin Christian J Wiedermann (Bolzano , Italy) Corticosteroids in 2014 [Standard presentation] The HPA axis is suppressed during critical illness Djillali Annane (Garches , France) The HPA axis is not suppressed during critical illness Greet Van Den Berghe (Leuven , Belgium) The problem is in the cell Clifford S Deutschman (Philadelphia , United States) Steroids in sepsis: do we need another trial? Balasubramanian Venkatesh (Brisbane , Australia) In ARDS? Djillali Annane (Garches , France) In severe CAP? Antoni Torres (Barcelona , Spain) In trauma? Jacques Duranteau (Le Kremlin-Bicêtre , France) Biomarkers in sepsis and ARDS [Standard presentation] Genome wide associated studies to define targets Didier Payen (Paris , France) Biomarkers in ARDS Arthur S Slutsky (Toronto , Canada) Biomarker discovery through proteomics Jean-Daniel Chiche (Paris , France) Biomarker discovery through metabolomics Greg S Martin (Atlanta , United States) Monitoring the immune system in sepsis Anthony McLean (Sydney , Australia) The utility of procalcitonin in critically ill septic patients Yahya Shehabi (Randwick, Australia) Procalcitonin to identify infection in heart failure Martin Möckel (Berlin, Germany) I am not sure PCT is sohelpful Mervyn Singer (London , United Kingdom) Alternative biomarkers Tommaso Mauri (Monza , Italy) Patient-ventilator dysynchrony [Standard presentation] Mechanisms Dimitris Georgopoulos (Heraklion , Greece) Recognition Marco Ranieri (Turin , Italy) We should mesure intratracheal pressure-swings Diederik Gommers (Rotterdam , Netherlands) It is harmful Robert M Kacmarek (Boston , United States) … maybe beneficial ? Laurent Brochard (Toronto, Canada) Managing the respirator Neil R MacIntyre (Durham , United States) Managing the patient Paolo Navalesi (Novara , Italy) Aim before you act: Defining a rational basis for selecting a ventilatory mode Robert Chatburn (Cleveland, United States) Partial ventilatory support [Standard presentation] Where are we now? Niall Ferguson (Toronto , Canada) Noisy ventilation Paolo Pelosi (Genoa , Italy) Ventilator-induced diaphragm dysfunction: Clinical impact Samir Jaber (Montpellier , France) How to improve diaphragm function Leo Heunks (Nijmegen , Netherlands) Current status of proportional-assist ventilation Dimitris Georgopoulos (Heraklion , Greece) Impact of APRV on oxygen delivery Brian Kavanagh (Toronto , Canada) Benefits of proportional modes Laurent Brochard (Toronto, Canada) NAVA in patients with ARDS Leo Heunks (Nijmegen , Netherlands) PAV and NAVA are ideal modes of ventilation Robert M Kacmarek (Boston , United States) How to reconcile the use of paralytics and the need to preserve muscular activity in ARDS Laurent Papazian (Marseille , France) Dealing with hypercapnia [Standard presentation] When to treat Andres Esteban (Madrid , Spain) A place for therapeutic hypercapnia? Brian Kavanagh (Toronto , Canada) ECCO2R in mechanical ventilation Michael Quintel (Göttingen , Germany) ECCO2R to avoid endotracheal intubation for decompensated COPD Marco Ranieri (Turin , Italy) ARDS is not a disease [Standard presentation] The Berlin definition is useful Niall Ferguson (Toronto , Canada) The Berlin definition is useless Robert M Kacmarek (Boston , United States) The Berlin definition is OK Greg S Martin (Atlanta , United States) Why have immunomodulation trials failed in ARDS? Neil R MacIntyre (Durham , United States) From the clinical to the molecular phenotype of ARDS José Angel Lorente (Madrid , Spain) Should we separate primary and secondary ARDS ? Andres Esteban (Madrid , Spain) Is ARDS different in children? Brian Kavanagh (Toronto , Canada) Biomarkers of ARDS: What, when and why? José Angel Lorente (Madrid , Spain) Quantitative diagnosis using extravascular lung water Takashi Tagami (Tokyo, Japan) Cell therapies [Standard presentation] Stem cells as markers of sepsis and ARDS Greg S Martin (Atlanta , United States) Mesenchymal stromal cells in sepsis Lauralyn McIntyre (Ottawa , Canada) Mesenchymal stromal cells for ARDS Taylor Thompson (Boston , United States) Stem cells in ARDS Paolo Pelosi (Genoa , Italy) VILI revisited [Standard presentation] Where does VILI start in the lungs? Luciano Gattinoni (Milan , Italy) PET: New questions and answers in dynamics of regional lung inflammation Fernando Suarez Sipmann (Uppsala, Sweden) Why young lungs are less sensitive Brian Kavanagh (Toronto , Canada) Lower tidal volumes for all? Marcus Schultz (Amsterdam , Netherlands) ….including in patients with cardiogenic shock? Karl Werdan (Halle , Germany) Why did we ever use large tidal volumes? Neil R MacIntyre (Durham , United States) Protective ventilation in non-injured lungs: Tidal volume, PEEP or both? Paolo Pelosi (Genoa , Italy) How to enhance lung protection during spontaneously breathing Tommaso Mauri (Monza , Italy) Novel approaches to minimize VILI Arthur S Slutsky (Toronto , Canada) ARDS: Prevention rather than cure [Standard presentation] ARDS can be largely prevented Ognjen Gajic (Rochester , United States) How can we prevent it? Gavin Perkins (Warwick , United Kingdom) The first week is crucial Andres Esteban (Madrid , Spain) The ARDS Network evolves to prevention Taylor Thompson (Boston , United States) Heart and lung [Standard presentation] Heart-lung interactions from the lung perspective Fernando Suarez Sipmann (Uppsala, Sweden) Cardiovascular insufficiency during initiation and withdrawal of mechanical ventilation Michael Pinsky (Pittsburgh , United States) Echocardiography to guide the management of pulmonary embolism Anthony McLean (Sydney , Australia) Inhaled therapies for right ventricular failure Sven-Erik Ricksten (Gothenburg, Sweden) Right ventricular protective ventilation Antoine Vieillard-Baron (Boulogne-Billancourt , France) Recruitment: When and how ? [Standard presentation] Bedside measurement Laurent Brochard (Toronto, Canada) Evaluation by imaging Davide Chiumello (Milan , Italy) Evaluation by electrical impedance tomography (EIT) Tommaso Mauri (Monza , Italy) Different methods, different effects? Paolo Pelosi (Genoa , Italy) Effect on cardiac function Michel Slama (Amiens , France) Is it safe?- Robert M Kacmarek (Boston , United States) It should be performed in every patient with ARDS: Yes Zsolt Molnar (Szeged , Hungary) It should be performed in every patient with ARDS: No Taylor Thompson (Boston , United States) Prone positioning in ARDS [Standard presentation] Prone positioning prevents VILI John J Marini (St Paul , United States) It also has beneficial hemodynamic effects Antoine Vieillard-Baron (Boulogne-Billancourt , France) In obese patients Samir Jaber (Montpellier , France) In intraabdominal hypertension Manu Malbrain (Antwerp , Belgium) High frequency ventilation: Is it passé ? [Standard presentation] What went wrong in the clinical trials? Niall Ferguson (Toronto , Canada) Are OSCILLATE and OSCAR the final words? Neil R MacIntyre (Durham , United States) I still use it in ARDS Jean-Daniel Chiche (Paris , France) So, is there still a place for high-frequency ventilation? Arthur S Slutsky (Toronto , Canada) Respiratory monitoring [Standard presentation] Lung imaging in ARDS Davide Chiumello (Milan , Italy) Electrical impedance tomography Jean-Michel Constantin (Clermont-Ferrand , France) Detection of pulmonary edema at the bedside Daniel Reuter (Hamburg , Germany) Chest X rays are obsolete, you only need echo Paul H Mayo (New York , United States) Should we measure transpulmonary pressure ? [Standard presentation] Why measure it ? Marco Ranieri (Turin , Italy) How to measure it ? Davide Chiumello (Milan , Italy) What are the limitations ? John J Marini (St Paul , United States) Does it improve outcomes ? Neil R MacIntyre (Durham , United States) Monitoring in mechanical ventilation [Standard presentation] Oxygen targets in mechanically ventilated patients Rinaldo Bellomo (Melbourne, Australia) How to monitor respiratory muscle function Leo Heunks (Nijmegen , Netherlands) How to monitor diaphragmatic function Niall Ferguson (Toronto , Canada) How to monitor lung mechanics Robert M Kacmarek (Boston , United States) The level of support based on EIT Diederik Gommers (Rotterdam , Netherlands) How monitoring can improve sleep Laurent Brochard (Toronto, Canada) PEEP titration [Standard presentation] Which is the best PEEP trial? Davide Chiumello (Milan , Italy) PEEP protects the lung by decreasing tidal volume Luciano Gattinoni (Milan , Italy) Balancing competing goals in setting PEEP Neil R MacIntyre (Durham , United States) Using transpulmonary pressures to adjust PEEP in ARDS Edgar Jimenez (Orlando , United States) EIT is able to apply the "best" PEEP Diederik Gommers (Rotterdam , Netherlands) Don’t forget the hemodynamic effects Antoine Vieillard-Baron (Boulogne-Billancourt , France) Role of dead space, the forgotten physiological measurement Fernando Suarez Sipmann (Uppsala, Sweden) Extracorporeal gas exchange [Standard presentation] ECMO retrieval team Alain Combes (Paris , France) ECMO: Latest fad or here to stay? Niall Ferguson (Toronto , Canada) ECCO2R in ARDS Antonio Pesenti (Milan , Italy) ECCO2R in severe asthma and COPD Christian Karagiannidis (Köln, Germany) Veno-venous ECMO: Nuts and boldts [Standard presentation] Which kind of cannulation? Alain Combes (Paris , France) Patient-ventilator interactions Antonio Pesenti (Milan , Italy) How to improve oxygenation during ECMO Bruno Levy (Vandoeuvre Les Nancy , France) Full blown high-flow ECMO: When and how Michael Quintel (Göttingen , Germany) Awake ECMO: Indications and limitations Tobias Welte (Hannover , Germany) Infections related to ECMO: How to recognize and treat Alain Combes (Paris , France) Pharmacokinetics during ECMO Fabio S Taccone (Brussels , Belgium) Should it be used only in reference centers? Laurent Papazian (Marseille , France) My idea is not so crazy [Standard presentation] Nitroprusside, lipids and estrogens in CPR Paul E Pepe (Dallas , United States) Inhaled NO to protect the brain Fumito Ichinose (Charlestown , United States) Suspended animation with hydrogen sulfide Mervyn Singer (London , United Kingdom) We should give EPO to all critically ill patients Peter Radermacher (Ulm , Germany) Breathomics to diagnose (almost) everything Marcus Schultz (Amsterdam , Netherlands) Take care when translating ´´clever´´ ideas Brian Kavanagh (Toronto , Canada) Challenges in intubation [Standard presentation] Only supraglottic airways in CPR? Jerry Nolan (Bath , United Kingdom) No place left for nasotracheal intubation? Eric Maury (Paris , France) Video laryngoscopy should be the preferred technique Paul H Mayo (New York , United States) We could do it better Samir Jaber (Montpellier , France) Tracheostomy early, late or never [Standard presentation] Minimizing risk during dilatational percutaneous tracheostomy Axel Nierhaus (Hamburg , Germany) How to do it better Paolo Pelosi (Genoa , Italy) Longer term outcomes Alain Combes (Paris , France) Patients like tracheostomy Marek Mirski (Baltimore , United States) Weaning [Standard presentation] Weaning - art or science? Georg-Christian Funk (Vienna , Austria) Failure of cardiac origin Xavier Monnet (Le Kremlin-Bicêtre , France) Failure from muscle weakness Andres Esteban (Madrid , Spain) NIV as a tool Gavin Perkins (Warwick , United Kingdom) Weaning and extubation in obese patients Samir Jaber (Montpellier , France) Do we need dedicated weaning centers? Jeremy M Kahn (Pittsburgh , United States) Non-invasive ventilation [Standard presentation] In the post-operative patient Samir Jaber (Montpellier , France) Should we always try it in COPD? Georg-Christian Funk (Vienna , Austria) For pneumonia Massimo Antonelli (Rome , Italy) For severe CAP Antoni Torres (Barcelona , Spain) In immunocompromised patients Dominique Benoit (Ghent , Belgium) How inflammatory markers can help Giuseppe Biondi-Zoccai (Rome, Italy) CPAP and NIV: Practical considerations [Standard presentation] NIV outside the ICU Paolo Navalesi (Novara , Italy) Non-invasive CPAP outside the ICU Paolo Pelosi (Genoa , Italy) Role of the upper airways in the success of NIV Leo Heunks (Nijmegen , Netherlands) Leak compensation: Invasive versus non-invasive ventilators Robert M Kacmarek (Boston , United States) Applying NIV by NAVA: Why, when and how Paolo Navalesi (Novara , Italy) What to do when NIV fails in a COPD Christian Karagiannidis (Köln, Germany) When is the right time to intubate? Andres Esteban (Madrid , Spain) Unless we have a do-not-intubate order? Elie Azoulay (Paris , France) How much oxygen ? [Standard presentation] Human tolerance of extreme hypoxemia Monty G Mythen (London , United Kingdom) Patient intolerance to hypoxemia Michael Quintel (Göttingen , Germany) Effects of hypoxia on the immune response Peter Pickkers (Nijmegen , Netherlands) Hyperoxia can be beneficial Peter Radermacher (Ulm , Germany) A place for hyperoxia in shock states Fuhong Su (Brussels , Belgium) Standardized approach to severe hypoxemia Ognjen Gajic (Rochester , United States) A place for permissive hypoxemia? Mervyn Singer (London , United Kingdom) Sedation & analgesia [Standard presentation] Moderators : Jean-Michel Constantin (Clermont-Ferrand , France) Trials of sedation have advanced our practice E Wesley Ely (Nashville , United States) Trials of sedation have contributed little Jukka Takala (Bern , Switzerland) Sedation strategies in the neuro-ICU Geert Meyfroidt (Leuven , Belgium) Ketamine is the best Paul Wischmeyer (Aurora , United States) Clonidine is ideal Patrice Forget (Brussels , Belgium) I'd like to sleep Dimitris Georgopoulos (Heraklion , Greece) A place for volatile anesthetics? Antonio Pesenti (Milan , Italy) Improved analgesia management may improve outcome Samir Jaber (Montpellier , France) Delirium [Standard presentation] Prevention Stephan A Mayer (New York , United States) Prediction Peter Pickkers (Nijmegen , Netherlands) Long-term outcomes E Wesley Ely (Nashville , United States) Early mobilization [Standard presentation] Moderators : Michael Ramsay (Dallas , United States) Getting ICU patients back to baseline Theodore J Iwashyna (Ann Arbor, United States) Muscle metabolism Greet Van Den Berghe (Leuven , Belgium) Physiotherapy for ICU-acquired weakness Evelyn Corner (London, United Kingdom) Do we need a trial on this? Paul Young (Wellington, New Zealand) We should mobilize both body and brain E Wesley Ely (Nashville , United States) Hemodynamic monitoring [Standard presentation] Bedside assessment of total cardiovascular status Michael Pinsky (Pittsburgh , United States) We can trust uncalibrated cardiac output monitors for the ICU : Yes Charles S Brudney (Durham , United States) We can trust uncalibrated cardiac output monitors for the ICU : No Xavier Monnet (Le Kremlin-Bicêtre , France) Widening patient access to flow monitoring from ICU to OR to general ward Max Jonas (Southampton , United Kingdom) Functional electrical impedance tomography Daniel Reuter (Hamburg , Germany) Determination of cardiac output by transthoracic echocardiography (TTE) Paolo Navalesi (Novara , Italy) Other non-invasive hemodynamic monitoring Andreas Hoeft (Bonn , Germany) Is there a place for these systems in the ICU? Matthieu Biais (Bordeaux, France) Accuracy and precision of the various cardiac output monitoring systems Maurizio Cecconi (London , United Kingdom) Hemodynamic monitoring: What’s the evidence . and does it matter? Azriel Perel (Tel Aviv , Israel) Hemodynamic monitoring - numbers to treat? Jukka Takala (Bern , Switzerland) Resuscitation towards the microcirculation [Standard presentation] Traditional resuscitation strategies and endpoints Lauralyn McIntyre (Ottawa , Canada) The microcirculation in obstructive and septic shock Jan Bakker (Rotterdam , Netherlands) Subcellular compartments: The glycocalyx and the mitochondria Can Ince (Amsterdam , Netherlands) CO2 tonometry in the ICU Didier Payen (Paris , France) We need to monitor tissue oxygenation Mervyn Singer (London , United Kingdom) Colloids vs crystalloids [Standard presentation] The physiologic basis Can Ince (Amsterdam , Netherlands) Is physiology wrong? Zsolt Molnar (Szeged , Hungary) How the type of fluid can influence immune status Didier Payen (Paris , France) HES storage: A comprehensive review Christian J Wiedermann (Bolzano , Italy) Does HES storage have pathophysiological relevance? Michael Joannidis (Innsbruck , Austria) Does HES really alter renal function? Claude Martin (Marseille , France) Why HES may increase mortality in sepsis Anders Perner (Copenhagen , Denmark) Could we develop new colloids? Jyrki Tenhunen (Uppsala, Sweden) Colloids are not dead! Djillali Annane (Garches , France) Type of fluids in various conditions [Standard presentation] In acute brain injury Peter Andrews (Edinburgh , United Kingdom) In trauma Andrew Shaw (Durham , United States) In ARDS Greg S Martin (Atlanta , United States) In the OR Gernot Marx (Aachen , Germany) In diabetic ketoacidosis Balasubramanian Venkatesh (Brisbane , Australia) In hepatorenal syndrome Pere Ginès (Barcelona, Spain) The end of saline solutions ? [Standard presentation] Saline is bad John Kellum (Pittsburgh , United States) The case for 0.9%NaCl Can Ince (Amsterdam , Netherlands) It is still OK to give normal saline: Yes Simon Finfer (Sydney , Australia) It is still OK to give normal saline: No Monty G Mythen (London , United Kingdom) We need a SPLIT trial Paul Young (Wellington, New Zealand) What should we study next? Paul Young (Wellington, New Zealand) Albumin [Standard presentation] Review of pharmacology Albert Farrugia (Perth, Australia) Metabolism in the severely ill Jan Wernerman (Stockholm , Sweden) Biological effects in cirrhosis Paolo Angeli (Padova , Italy) Albumin for resuscitation Lauralyn McIntyre (Ottawa , Canada) Albumin supplementation Massimo Antonelli (Rome , Italy) The Albios study: Resuscitation and/or supplementation Luciano Gattinoni (Milan , Italy) How much fluid? [Standard presentation] When do we need a fluid challenge? Jean-Louis Vincent (Brussels , Belgium) How do we guide it? The Fenice study Daniel De Backer (Brussels , Belgium) The hemodynamic effects of a fluid bolus Rinaldo Bellomo (Melbourne, Australia) How to monitor the effects of fluid administration Xavier Monnet (Le Kremlin-Bicêtre , France) The use of mean systemic filling pressure in fluid resuscitation Jan Bakker (Rotterdam , Netherlands) How to assess preload in intraabdominal hypertension Jan De Waele (Ghent , Belgium) Fluid balance in severe sepsis: The lower the better? Yasser Sakr (Jena , Germany) Could rapid determination of plasma volume help? Bruce A Molitoris (Indianapolis , United States) Fluid resuscitation should be guided by . [Standard presentation] Fluid responsiveness Jean-Louis Teboul (Le Kremlin-Bicêtre , France) Cardiac output and/or stroke volume Michael Sander (Berlin , Germany) Urine analysis Luciano Gattinoni (Milan , Italy) ScvO2 Stephen Trzeciak (Camden , United States) Extravascular lung water Mikhail Kirov (Arkhangelsk , Russia) The peripheral circulation Jan Bakker (Rotterdam , Netherlands) The microcirculation Daniel De Backer (Brussels , Belgium) The pros and cons of fluid responsiveness [Standard presentation] Pulse pressure vs stroke volume variation Maurizio Cecconi (London , United Kingdom) Assessment in spontaneously breathing patients Xavier Monnet (Le Kremlin-Bicêtre , France) Can we use non-invasive tools? Patrice Forget (Brussels , Belgium) How it's affected by patient-ventilator synchrony Paolo Navalesi (Novara , Italy) Limitations of using pulse pressure variation Michel Slama (Amiens , France) Fluid unresponsiveness should be avoided Jan Bakker (Rotterdam , Netherlands) In the emergency room [Standard presentation] Overcrowding Martin Möckel (Berlin, Germany) Risk stratification with biomarkers Christian H Nickel (Basel , Switzerland) Critical care ultrasonography of the whole body Paul H Mayo (New York , United States) The battered child Philippe Jorens (Edegem , Belgium) Drugs of abuse: A shifting landscape Janice L. Zimmerman (Houston , United States) Intoxications: Indications for extracorporeal support Patrick Honoré (Brussels , Belgium) Risk stratification in burn injury Stijn Blot (Ghent , Belgium) Anaphylaxis Jerrold H Levy (Durham, United States) Neurologic emergencies [Standard presentation] Mannitol vs hypertonic saline for cerebral edema Marek Mirski (Baltimore , United States) Call the neurosurgeon now Peter Le Roux (Wynnewood, United States) Endovascular therapy for stroke Stephan A Mayer (New York , United States) Status epilepticus Mauro Oddo (Lausanne , Switzerland) Severe heart failure [Standard presentation] Optimal vasopressor use Bruno Levy (Vandoeuvre Les Nancy , France) Still a place for balloon pump? Karl Werdan (Halle , Germany) Routine use of ultrafiltration? Amir Kazory (Gainesville, United States) High volume hemofiltration is HEROIC Alain Combes (Paris , France) Diastolic dysfunction: What to do about it? Jan Poelaert (Brussels , Belgium) Cardiovascular alterations in sepsis [Standard presentation] Basics of vascular hyporesponsiveness in septic shock Bruno Levy (Vandoeuvre Les Nancy , France) Basics of septic cardiomyopathy Andreas Hoeft (Bonn , Germany) Systolic and/or diastolic function Michel Slama (Amiens , France) Does it really matter? Antoine Vieillard-Baron (Boulogne-Billancourt , France) Does it really predict outcome? Anthony McLean (Sydney , Australia) High risk surgery [Standard presentation] How big is the problem? Berthold Bein (Kiel , Germany) Enhanced recovery after surgery Monty G Mythen (London , United Kingdom) Intraoperative risk assessment Stefan De Hert (Ghent , Belgium) Prevention of perioperative aspiration Jan Poelaert (Brussels , Belgium) Ventilator management during surgery Paolo Pelosi (Genoa , Italy) Ventilatory management of the obese perioperative patient Samir Jaber (Montpellier , France) Postoperative respiratory depression can be harmful Michael Ramsay (Dallas , United States) Improving outcomes for emergency laparotomy Nial Quiney (Guildford , United Kingdom) Preventing renal failure after cardiac surgery Alain Combes (Paris , France) Detecting complications outside the ICU Andreas Hoeft (Bonn , Germany) Long-term effects of postoperative complications Maurizio Cecconi (London , United Kingdom) Goal-directed perioperative optimization [Standard presentation] Current status Andrew Rhodes (London , United Kingdom) Options for cardiac output monitoring Simon Davies (York, United Kingdom) Fluid management Monty G Mythen (London , United Kingdom) The unanswered questions Azriel Perel (Tel Aviv , Israel) Traumatic brain injury [Standard presentation] Oxygen therapy and ventilator management Peter Andrews (Edinburgh , United Kingdom) Fever control Paul Young (Wellington, New Zealand) Imaging Paul Vespa (Los Angeles , United States) Neuromonitoring Peter Le Roux (Wynnewood, United States) Raised ICP - a thing of the past? Peter Andrews (Edinburgh , United Kingdom) Intracranial hypertension can be largely prevented Geert Meyfroidt (Leuven , Belgium) When is aggressive therapy required? Nino Stocchetti (Milan , Italy) Time is critical Marek Mirski (Baltimore , United States) Therapeutic hypothermia [Standard presentation] Host response Nicole Juffermans (Amsterdam , Netherlands) Metabolic effects Arthur Van Zanten (Ede , Netherlands) Temperature management in trauma: Warm, cool, or inbetween? Michael Reade (Herston QLD, Australia) Brain cooling: Challenges and potential rewards Peter Andrews (Edinburgh , United Kingdom) Pitfalls of rewarming Janice L. Zimmerman (Houston , United States) Neuromonitoring [Standard presentation] Inside the black box: Brain multimodality monitoring Stephan A Mayer (New York , United States) Brain oxygen and metabolism in neurocritical care Peter Le Roux (Wynnewood, United States) Hemodynamic monitoring Fabio S Taccone (Brussels , Belgium) Spreading depolarizations Raimund Helbok (Innsbruck , Austria) Can we reach a consensus? Giuseppe Citerio (Monza , Italy) Neurological challenges [Standard presentation] Autoimmune encephalitis Raimund Helbok (Innsbruck , Austria) Refractory status epilepticus Stephan A Mayer (New York , United States) Neurogenic pulmonary edema Lakhmir Chawla (Washington , United States) Septic encephalopathy Fabio S Taccone (Brussels , Belgium) Intracerebral hemorrhage [Standard presentation] Stop the bleeding Stephan A Mayer (New York , United States) Optimal blood pressure Paul Vespa (Los Angeles , United States) Conservative treatment Nino Stocchetti (Milan , Italy) When to operate Peter Le Roux (Wynnewood, United States) Subarachnoid hemorrhage: New Strategies [Standard presentation] Early brain injury Raimund Helbok (Innsbruck , Austria) Delayed ischemia Nino Stocchetti (Milan , Italy) Vasospasm management Peter Le Roux (Wynnewood, United States) Coagulopathies [Standard presentation] Update on HIT Jerrold H Levy (Durham, United States) Utility of TEG/ROTEM to detect hypercoagulability in ICU patients Nicole Juffermans (Amsterdam , Netherlands) von Willebrand factor in critical care Beverley Hunt (London , United Kingdom) In sepsis Tom van der Poll (Amsterdam , Netherlands) In liver disease Julia Wendon (London , United Kingdom) A place for fresh frozen plasma in the non-bleeding patient Janice L. Zimmerman (Houston , United States) Is it necessary to correct coagulopathy prior to an invasive procedure? Nicole Juffermans (Amsterdam , Netherlands) Dealing with old and new antithrombotics [Standard presentation] Reversing the effects of vitamin K antagonists Truman Milling (Austin, United States) New oral anticoagulants: The evolving story Beverley Hunt (London , United Kingdom) Use of new oral anticoagulants Jerrold H Levy (Durham, United States) Oral anticoagulant-induced bleeding Christian J Wiedermann (Bolzano , Italy) Antagonizing the effects of oral antiplatelet agents Giuseppe Biondi-Zoccai (Rome, Italy) Massive bleeding [Standard presentation] Pathophysiology of hemorrhagic shock Matthieu Biais (Bordeaux, France) Obstetric hemorrhage Beverley Hunt (London , United Kingdom) Bleeding complications in sepsis Anders Perner (Copenhagen , Denmark) How much FFP? Kai Zacharowski (Frankfurt , Germany) How many platelet transfusions? Michael Hiesmayr (Vienna , Austria) Fibrinogen to boost coagulation? Jacques Duranteau (Le Kremlin-Bicêtre , France) Tranexamic acid: More than an antifibrinolytic drug? Beverley Hunt (London , United Kingdom) Desmopressin? Giovanni Landoni (Milan, Italy) A summary of our new concepts Jerrold H Levy (Durham, United States) A place for fresh blood against blood bank policies? Albert Farrugia (Perth, Australia) Transfusion [Standard presentation] Non-bleeding causes of anemia Peter Pickkers (Nijmegen , Netherlands) Patient blood management: A clinical trial Kai Zacharowski (Frankfurt , Germany) Review of transfusion triggers in the critically ill Lauralyn McIntyre (Ottawa , Canada) The beneficial effects of blood transfusions Can Ince (Amsterdam , Netherlands) 7 g/dL threshold for all? Yasser Sakr (Jena , Germany) 10 g/dL threshold for some Marek Mirski (Baltimore , United States) Triggers in neurocritical care Peter Le Roux (Wynnewood, United States) Triggers in coronary artery disease Philippe Van Der Linden (Brussels , Belgium) Triggers in septic shock Anders Perner (Copenhagen , Denmark) ScvO2 and CO2-gap as triggers Zsolt Molnar (Szeged , Hungary) Does age of blood matter? Lauralyn McIntyre (Ottawa , Canada) Polytrauma [Standard presentation] Hemodynamic monitoring Jacques Duranteau (Le Kremlin-Bicêtre , France) Abdominal trauma John C Marshall (Toronto , Canada) Pelvic fracture Jacques Duranteau (Le Kremlin-Bicêtre , France) Liver trauma Julia Wendon (London , United Kingdom) Quality indicators Michael Reade (Herston QLD, Australia) VAP [Standard presentation] Are ventilator-associated events different from VAP? Yes Robert M Kacmarek (Boston , United States) Are ventilator-associated events different from VAP? No Clifford S Deutschman (Philadelphia , United States) Update on VAP management Michael S Niederman (Mineola , United States) VAP as a source of antimicrobial overuse Jean Chastre (Paris , France) Inhaled antibiotics for VAP: The next major breakthrough? Marin Kollef (St Louis , United States) Maybe not Tobias Welte (Hannover , Germany) Is it time to develop new guidelines? Antoni Torres (Barcelona , Spain) VAP: Preventive measures [Standard presentation] Mod Tommaso Mauri (Monza , Italy) How much is preventable? Marin Kollef (St Louis , United States) Prevention by oral care Stijn Blot (Ghent , Belgium) Mucus flow and physiotherapy Antoni Torres (Barcelona , Spain) Liver failure [Standard presentation] Acute liver failure: Syndromes and management Julia Wendon (London , United Kingdom) Acute-on-chronic Pere Ginès (Barcelona, Spain) Perioperative management Michael Ramsay (Dallas , United States) Feeding the cirrhotic patient Pierre-François Laterre (Brussels , Belgium) Renal failure in cirrhosis Paolo Angeli (Padova , Italy) Liver dialysis: Quo vadis? Alexander Wilmer (Leuven , Belgium) Pancreatitis [Standard presentation] Basic principles in managing a complex disease John C Marshall (Toronto , Canada) Cardiovascular management Daniel Reuter (Hamburg , Germany) Respiratory management Samir Jaber (Montpellier , France) Early enteral feeding for all? Stephen McClave (Louisville, United States) When to give antibiotics and antifungals Philippe Montravers (Paris , France) Nutritional support [Standard presentation] Nutrition and autophagy during critical illness Greet Van Den Berghe (Leuven , Belgium) How stress influences the gut Pierre Déchelotte (Rouen , France) Malnutrition and outcomes Kenneth Christopher (Boston, United States) Refeeding syndrome in the ICU Michael Hiesmayr (Vienna , Austria) Obesity and outcome Yasser Sakr (Jena , Germany) Malabsorption of nutrients in the critically ill Adam Deane (Adelaide , Australia) Fasting as a risk factor for adverse renal outcomes? Ravindra Mehta (San Diego , United States) Enteral and/or parenteral routes: Resolving controversies Paul Wischmeyer (Aurora , United States) Not all ICU patients will benefit Daren K Heyland (Kingston , Canada) When is permissive underfeeding appropriate? Stephen McClave (Louisville, United States) Special nutrients [Standard presentation] Glutamine and antioxidants: An update Daren K Heyland (Kingston , Canada) Glutamine supplementation should now be avoided Arthur Van Zanten (Ede , Netherlands) The role of omega-3 fatty acid, gamma-linolenic acid, and antioxidant supplementation Taylor Thompson (Boston , United States) Still a place for anti-oxidants? Paul Van Leeuwen (Amsterdam , Netherlands) Adding vitamin D for everyone? Kenneth Christopher (Boston, United States) How to assess the risks of special nutrients Jean-Charles Preiser (Brussels , Belgium) Protein is the most important nutrient in the ICU Paul Wischmeyer (Aurora , United States) Nutritional support in special circumstances [Standard presentation] In the critically ill obese Paul Wischmeyer (Aurora , United States) In acute renal failure Enrico Fiaccadori (Parma , Italy) In pancreatitis Pierre-François Laterre (Brussels , Belgium) In cirrhosis Julia Wendon (London , United Kingdom) Glucose control in 2014 [Standard presentation] Glucose: A pro-inflammatory substrate Didier Payen (Paris , France) Has anything happened since NICE-SUGAR? James Krinsley (Stamford , United States) Intensive insulin therapy trialists’ collaboration: A meta-analysis of individual data Simon Finfer (Sydney , Australia) Similar targets after acute brain injury? Mauro Oddo (Lausanne , Switzerland) What about diabetics? James Krinsley (Stamford , United States) Near-continuous glucose monitoring Jean-Charles Preiser (Brussels , Belgium) Pharmaconutrition and insulin resistance Pierre Déchelotte (Rouen , France) Novel therapies to treat hyperglycemia without causing hypoglycemia Adam Deane (Adelaide , Australia) Enteral nutrition [Standard presentation] Swallowing disorders: A treatable risk factor Michael Hiesmayr (Vienna , Austria) Early enteral nutrition: Does the route matter? Stephen McClave (Louisville, United States) Feeding in the jejunum is better than in the stomach Paul Van Leeuwen (Amsterdam , Netherlands) Intragastric versus small intestinal delivery Adam Deane (Adelaide , Australia) Importance of high-protein enteral nutrition Arthur Van Zanten (Ede , Netherlands) Energy requirements: How early and how much? [Standard presentation] Calculating energy needs in critically ill patients: Sense or nonsense? Herbert Spapen (Brussels , Belgium) Should we use indirect calorimetry in the ICU Stephen McClave (Louisville, United States) How to define caloric needs Jean-Charles Preiser (Brussels , Belgium) Antimicrobial strategies [Standard presentation] Death by antibiotic Richard Wunderink (Chicago , United States) A review of recent anti-Gram-positive drugs Robert Masterton (Ayrshire, United Kingdom) A recent review of anti-Gram negative drugs Mark Wilcox (Leeds , United Kingdom) Optimizing therapy with beta-lactam antibiotics Jan De Waele (Ghent , Belgium) Have we outsmarted ourselves with PK/PD optimization Richard Wunderink (Chicago , United States) Brain toxicity of beta-lactams Fabio S Taccone (Brussels , Belgium) Combination antibiotic therapy Thierry Calandra (Lausanne , Switzerland) Mono versus bi-therapy in Pseudomonas infections Jean Chastre (Paris , France) De-escalation of antibiotic treatment for all Claude Martin (Marseille , France) De-escalation is not always possible Jan De Waele (Ghent , Belgium) Duration of antibiotic therapy Jean-François Timsit (Paris, France) Infectious threats - Pandemics [Standard presentation] Emerging infectious diseases in a shrinking world Thierry Calandra (Lausanne , Switzerland) Developing quick diagnostic tests Richard Rothman (Baltimore, United States) How the critical care community should react John C Marshall (Toronto , Canada) Personal protective strategies Edgar Jimenez (Orlando , United States) Disasters [Standard presentation] Ready for the next disaster? Paul E Pepe (Dallas , United States) Wounds to expect after an explosion Michael Reade (Herston QLD, Australia) Emergency mass critical care Niranjan (Tex) Kissoon (Vancouver , Canada) ICU preparedness in mass casualty incidents Edgar Jimenez (Orlando , United States) Nosocomial infections [Standard presentation] Rapid molecumar testing Richard Rothman (Baltimore, United States) The microbial flora of critical illness: What does it tell us? John C Marshall (Toronto , Canada) Chlorhexidine: Anyone for a bath? Mark Wilcox (Leeds , United Kingdom) A place for probiotics in critical care? Paul Wischmeyer (Aurora , United States) Hospital-acquired pneumonia Richard Wunderink (Chicago , United States) Prevention of catheter-related infections Jean-François Timsit (Paris, France) Adenovirus infections François Simon (Paris, France) An algorithm to treat healthcare-associated pneumonia in the ICU Michael S Niederman (Mineola , United States) Multiresistant organisms [Standard presentation] Risk factors for MDR pathogens in the ICU Michael S Niederman (Mineola , United States) C. difficile infection: Where next? Mark Wilcox (Leeds , United Kingdom) Recent infection control developments in the ICU Robert Masterton (Ayrshire, United Kingdom) Multidrug resistance strains in intraabdominal infections Philippe Montravers (Paris , France) New technologies for infection diagnostics François Simon (Paris, France) Early recognition of resistant bacteria Robert Bonomo (Cleveland, United States) Intelligent use of antibiotics to limit antibiotic resistance Steven Opal (Providence , United States) Antibiotic treatment in the era of MDR pathogens Tobias Welte (Hannover , Germany) How to treat carbapenemase-producing enterobacteriaceae? Matteo Bassetti (Udine, Italy) How to use colistin? Arthur Van Zanten (Ede , Netherlands) Aerosolized antibiotics for resistant organisms Massimo Antonelli (Rome , Italy) What new antibiotics are in the pipeline? Matteo Bassetti (Udine, Italy) Viral and fungal infections [Standard presentation] Herpes simplex in the ICU Philippe Jorens (Edegem , Belgium) Should we treat cytomegalovirus reactivation? Laurent Papazian (Marseille , France) Sepsis in HIV patients Tom van der Poll (Amsterdam , Netherlands) Candida sepsis Thierry Calandra (Lausanne , Switzerland) Intra-abdominal candidiasis: Management recommendations Matteo Bassetti (Udine, Italy) Candida infection: Epidemiology and markers Antonio Messias (Loures, Portugal) Role of biomarker-based pre-emptive antifungal therapy Markus Ruhnke (Berlin , Germany) The importance of empiric therapy for Candida in nosocomial septic shock Marin Kollef (St Louis , United States) Candida in the lung: Should we treat it? Daren K Heyland (Kingston , Canada) Aspergillus infections in the ICU Elie Azoulay (Paris , France) Bicarbonate administration: A reappraisal [Standard presentation] In severe lactic acidosis Bruno Levy (Vandoeuvre Les Nancy , France) In non-lactic metabolic acidosis Patrick Honoré (Brussels , Belgium) In respiratory acidosis Antonio Pesenti (Milan , Italy) To protect the kidney Rinaldo Bellomo (Melbourne, Australia) Electrolyte and acid-base [Standard presentation] A new look at dysnatremia Michael Darmon (Saint-Priest-en-Jarez, France) Biomarkers for the differential diagnosis of hyponatremia Mirjam Christ-Crain (Basel, Switzerland) Management of hyponatremia - Guidelines Djillali Annane (Garches , France) Magnesium: The forgotten ion Figen Esen (Istanbul , Turkey) Chloride: The key electrolyte in acid-base control Luciano Gattinoni (Milan , Italy) Metabolic alkalosis Enrico Fiaccadori (Parma , Italy) Monitoring the kidney [Standard presentation] The continuing spectrum from mild pre-renal to end-stage renal failure Claudio Ronco (Vicenza , Italy) Cell cycle arrest biomarkers John Kellum (Pittsburgh , United States) Novel biomarkers Rinaldo Bellomo (Melbourne, Australia) Renal biomarkers: How to use them in practice Andrew Shaw (Durham , United States) Measured GFR: Is it useful? Bruce A Molitoris (Indianapolis , United States) Assessment of renal perfusion using renal Doppler Michael Darmon (Saint-Priest-en-Jarez, France) Contrast-enhanced ultrasound Jacques Duranteau (Le Kremlin-Bicêtre , France) The renal stress test Lakhmir Chawla (Washington , United States) The injured kidney [Standard presentation] The renal microcirculation in sepsis Can Ince (Amsterdam , Netherlands) A role for adenosine receptor agonists and antagonists? Patrick Honoré (Brussels , Belgium) How the kidneys recover Miet Schetz (Leuven , Belgium) Preventing renal failure [Standard presentation] Protection of renal function in the ICU Michael Joannidis (Innsbruck , Austria) How to improve renal perfusion, filtration and oxygenation Sven-Erik Ricksten (Gothenburg, Sweden) Biomarkers to define the pathophysiology Michael Joannidis (Innsbruck , Austria) Validation of a risk score Ravindra Mehta (San Diego , United States) In high-risk surgical patients Yahya Shehabi (Randwick, Australia) Fenoldopam in renal protection Giovanni Landoni (Milan, Italy) Contrast induced nephropathy: Does anything work? Claudio Ronco (Vicenza , Italy) My checklist Eric Hoste (Ghent , Belgium) Renal replacement therapy [Standard presentation] Would outcomes be worse without renal replacement therapy? Sean Bagshaw (Edmonton , Canada) Optimal timing John Kellum (Pittsburgh , United States) Should we start earlier in the presence of lactate-associated acidosis? Eric Hoste (Ghent , Belgium) Does the type of RRT influence renal recovery?- Rinaldo Bellomo (Melbourne, Australia) How to prescribe the appropriate dose and type of fluids Claudio Ronco (Vicenza , Italy) Permissive hypofiltration Lakhmir Chawla (Washington , United States) Optimizing hemodynamic stability during RRT Ravindra Mehta (San Diego , United States) SLED in the ICU Enrico Fiaccadori (Parma , Italy) My protocol for citrate anticoagulation Miet Schetz (Leuven , Belgium) Citrate anticoagulation: Not for every case Patrick Honoré (Brussels , Belgium) Regional citrate vs heparin anticoagulation: A new study David Gattas (Sydney , Australia) Extracorporeal therapies in sepsis [Standard presentation] They are useless Miet Schetz (Leuven , Belgium) The Abdomix study Didier Payen (Paris , France) Combined plasma filtration and adsorption (CPFA) may be valuable Giorgio Berlot (Trieste , Italy) High volume hemofiltration: Good or bad? Michael Joannidis (Innsbruck , Austria) CPR [Standard presentation] No ventilation CPR Paul E Pepe (Dallas , United States) Is it worthwhile attempting CPR in traumatic cardiac arrest? Michael Reade (Herston QLD, Australia) Update on mechanical chest compression devices Kjetil Sunde (Oslo , Norway) Impedance threshold devices for CPR: Fact or fiction? Giuseppe Biondi-Zoccai (Rome, Italy) Ventilation during CPR Laurent Brochard (Toronto, Canada) What we know about defibrillation today Lars Wik (Oslo, Norway) Should we still use epinephrine? Jerry Nolan (Bath , United Kingdom) Percutaneous circulatory support in CPR Michael Fries (Aachen , Germany) Should we rescue out-of-hospital cardiac arrest with ECMO? Alain Combes (Paris , France) Improving quality through feedback and debriefing Gavin Perkins (Warwick , United Kingdom) The fifth link in the “Chain of Survival” concept Takashi Tagami (Tokyo, Japan) Is there a role for ‘cardiac arrest centers’? Jerry Nolan (Bath , United Kingdom) The future of CPR [Standard presentation] Stutter CPR Paul E Pepe (Dallas , United States) Hydrogen sulfide as a life-saver Fumito Ichinose (Charlestown , United States) Post-cardiac arrest care: Future roads Niklas Nielsen (Helsingborg, Sweden) After cardiac arrest [Standard presentation] Immediate coronary angiography after all cardiac arrests?: Yes Giuseppe Biondi-Zoccai (Rome, Italy) Immediate coronary angiography after all cardiac arrests?: No Kjetil Sunde (Oslo , Norway) Respiratory care: What are the targets? Niklas Nielsen (Helsingborg, Sweden) Oxygen and carbon dioxide management following cardiac arrest Paul Young (Wellington, New Zealand) New therapeutic measures to improve organ function Stephen Trzeciak (Camden , United States) Postanoxic brain damage [Standard presentation] Prognostication Massimo Antonelli (Rome , Italy) New biomarkers Michael Joannidis (Innsbruck , Austria) New data on biomarkers Hans Friberg (Lund , Sweden) Place of EEG Hans Friberg (Lund , Sweden) Multimodal prognostication Mauro Oddo (Lausanne , Switzerland) Measuring consciousness with a number Steven Laureys (Liège , Belgium) Protecting the brain after cardiac arrest [Standard presentation] Will fast and early cooling further improve survival? Kjetil Sunde (Oslo , Norway) Target temperature: 33 vs 36°C Niklas Nielsen (Helsingborg, Sweden) Should non-VF arrest patients be cooled? Kjetil Sunde (Oslo , Norway) Optimal blood pressure Fabio S Taccone (Brussels , Belgium) Optimal heart rate Kjetil Sunde (Oslo , Norway) Optimal ventilator strategy Jyrki Tenhunen (Uppsala, Sweden) Xenon in combination with hypothermia Michael Fries (Aachen , Germany) Novel neuroprotective strategies Fumito Ichinose (Charlestown , United States) What is the overall outcome? Hans Friberg (Lund , Sweden) Rapid response systems [Standard presentation] Automated triggering? Jyrki Tenhunen (Uppsala, Sweden) Routine lab test to identify at risk patients Rinaldo Bellomo (Melbourne, Australia) The nurses are the best trigger Arthur Van Zanten (Ede , Netherlands) An electronic early warning system to improve outcomes in hospitalized patients Marin Kollef (St Louis , United States) A new Australian study David Gattas (Sydney , Australia) Rescue of medically deteriorating patients Naeem Ali (Columbus , United States) Proactive systems: How to implement the next generation? Edgar Jimenez (Orlando , United States) Implementing a rapid response system in your hospital Ken Hillman (Liverpool , Australia) After the ICU [Standard presentation] Continuity of care in critical care Naeem Ali (Columbus , United States) Burden of chronic critical illness Stephen Trzeciak (Camden , United States) Long term sequelae of sepsis Derek C Angus (Pittsburgh , United States) MRI findings after severe ARDS Michael Quintel (Göttingen , Germany) Outcomes of the very elderly Daren K Heyland (Kingston , Canada) Recovery from cachexia: Can we learn from athletes? Paul Wischmeyer (Aurora , United States) Obesity is an advantage Peter Pickkers (Nijmegen , Netherlands) The Chelsea Critical Care Physical Assessment tool (CPAx) to measure functional recovery Evelyn Corner (London, United Kingdom) Acquired dementia following ICU stay E Wesley Ely (Nashville , United States) Long-term outcomes: How is it fixable? Gordon Rubenfeld (Toronto , Canada) Organ donation [Standard presentation] End-of-life electrical spikes: Separating fact from fiction Lakhmir Chawla (Washington , United States) Management of the potential organ donor Giuseppe Citerio (Monza , Italy) Goal-directed resuscitation John Kellum (Pittsburgh , United States) Increasing the number of lungs for transplantion Arthur S Slutsky (Toronto , Canada) Managing the lung donor Marco Ranieri (Turin , Italy) Managing the liver donor Julia Wendon (London , United Kingdom) New approaches to clinical trials [Standard presentation] What multicenter RCTs show a reduced mortality in the critically ill patients? Giovanni Landoni (Milan, Italy) Sepsis outcomes: How much is due to the patient, the hospital, or the health system? Theodore J Iwashyna (Ann Arbor, United States) New study designs in sepsis Derek C Angus (Pittsburgh , United States) We need a core outcome measure set for acute care research (COMET) John C Marshall (Toronto , Canada) Cluster RCTs Rinaldo Bellomo (Melbourne, Australia) Still struggling with attributable mortality Jean-François Timsit (Paris, France) Acute physiological responsiveness: A criterion for trial entry? Brian Kavanagh (Toronto , Canada) Acute sepsis MODS vs chronic critical illness Clifford S Deutschman (Philadelphia , United States) QALYs as an outcome Niall Ferguson (Toronto , Canada) Neurological testing and quality of life Niklas Nielsen (Helsingborg, Sweden) ARDS as an end-point Taylor Thompson (Boston , United States) To what extent can we use surrogate markers? Antoni Torres (Barcelona , Spain) The value of observational studies James Krinsley (Stamford , United States) The role of data safety and monitoring boards Arthur S Slutsky (Toronto , Canada) Trials and tribulations of pre-hospital CPR trials Gavin Perkins (Warwick , United Kingdom) Feasible endpoints for clinical trials Michael Reade (Herston QLD, Australia) Guidelines and bundles [Standard presentation] Medical informatics to guide therapy Paul Vespa (Los Angeles , United States) Using apps as a support Martin Möckel (Berlin, Germany) AWARE and CERTAIN: Novel intelligence application Ognjen Gajic (Rochester , United States) Pros and cons of protocols Brian Kavanagh (Toronto , Canada) The NICE experience: Influence of committees and politicians Max Jonas (Southampton , United Kingdom) Improving compliance with sepsis guidelines Niranjan (Tex) Kissoon (Vancouver , Canada) The hemodynamic recommendations of the Surviving Sepsis Campaign are simply unacceptable Azriel Perel (Tel Aviv , Israel) How come hospitals that care for more sepsis patients may not produce better outcomes? Theodore J Iwashyna (Ann Arbor, United States) Quality improvement through education: The MEDUSA trial Konrad Reinhart (Jena , Germany) What about guideline adherence in cardiogenic shock therapy? Karl Werdan (Halle , Germany) What would you do when there is little evidence? Gordon Rubenfeld (Toronto , Canada) How to improve ICU quality [Standard presentation] How to select your computer-information management systel Jean-Daniel Chiche (Paris , France) A user's guide to quality metrics Theodore J Iwashyna (Ann Arbor, United States) Improving quality through benchmarking Leo Anthony Celi (Cambridge, United States) Is readmission to the ICU a good quality measure? Jeremy M Kahn (Pittsburgh , United States) Regionalization of care Mitchell Levy (Providence , United States) How structure, process and organization impact ICU outcomes Greg S Martin (Atlanta , United States) ICU staffing [Standard presentation] Impact of ICU staffing and organization on outcomes Derek C Angus (Pittsburgh , United States) Do nighttime intensivists make a difference? Mitchell Levy (Providence , United States) Will we all hire advance practice providers in the ICU? Jeremy M Kahn (Pittsburgh , United States) ICU telemedicine: Panacea or placebo? Jeremy M Kahn (Pittsburgh , United States) Many strategies for cost containment are not cost saving Gordon Rubenfeld (Toronto , Canada) Can we still learn from autopsy? [Standard presentation] Unexpected findings in critically ill patients: The role of autopsy Giorgio Berlot (Trieste , Italy) Thanatology scanner: Autopsy today Eric Maury (Paris , France) Histological changes associated with organ dysfunction José Angel Lorente (Madrid , Spain) Public awareness [Standard presentation] Communicating about sepsis Konrad Reinhart (Jena , Germany) How to talk to the public Paul E Pepe (Dallas , United States) Should public reporting be mandatory? Mitchell Levy (Providence , United States) Improving rounds in the ICU [Standard presentation] How to cope with moral distress in the team Janice L. Zimmerman (Houston , United States) The 10 rules of successful rounds JL Vincent Jean-Louis Vincent (Brussels , Belgium) Inviting the family to join ICU rounds: Folly or the future? Taylor Thompson (Boston , United States) Interruptions during ward rounds: Necessary evil or a nuisance Balasubramanian Venkatesh (Brisbane , Australia) Rounds by telemedicine? Paul Vespa (Los Angeles , United States) Intensive care around the globe [Standard presentation] A tale of 7 cities Derek C Angus (Pittsburgh , United States) Intensive care in Asia Development of critical care medicine in the Asia-Pacific region Anthony McLean (Sydney , Australia) Implementing cheap but effective ICUs in lower income countries Marcus Schultz (Amsterdam , Netherlands) Critical care is very cost-effective in developing countries Ognjen Gajic (Rochester , United States) The global burden of sepsis Konrad Reinhart (Jena , Germany) Sepsis internationally: I am IMPRESSed Mitchell Levy (Providence , United States) Surviving sepsis in resource limited environments Niranjan (Tex) Kissoon (Vancouver , Canada) There are disparities in critical care in each country Kenneth Christopher (Boston, United States) Workforce issues in intensive care: A global perspective Balasubramanian Venkatesh (Brisbane , Australia) End-of-life care [Standard presentation] Diagnosing dying: A new role for intensivists Ken Hillman (Liverpool , Australia) We do not know enough about patients’ preferences? Daren K Heyland (Kingston , Canada) Antibiotics should be withheld in terminally ill patients Michael S Niederman (Mineola , United States) The use of futility is futile Jan Bakker (Rotterdam , Netherlands) The prolonged critically ill patient: How to stay motivated Geert Meyfroidt (Leuven , Belgium) A hard Canadian experience Gordon Rubenfeld (Toronto , Canada) Do we need palliative care specialists? Michael Quintel (Göttingen , Germany) Extubation or terminal weaning? Jean Reignier (La Roche Sur Yon Cedex 9 , France) Palliative sedation Steven Laureys (Liège , Belgium) How to provide a "good death" E Wesley Ely (Nashville , United States) Denied ICU admissions [Standard presentation] New admission policies for cancer patients Elie Azoulay (Paris , France) The patient is too old Bertrand Guidet (Paris , France) The patient is too frail Sean Bagshaw (Edmonton , Canada) Pro/con Fluid loading [Standard presentation] Fluid administration should be generous Daniel De Backer (Brussels , Belgium) Fluid administration should be restricted Simon Finfer (Sydney , Australia) Does quantity really matter? Lauralyn McIntyre (Ottawa , Canada) Fluid and the kidney [Standard presentation] The acute hemodynamic effects of furosemide Rinaldo Bellomo (Melbourne, Australia) Are diuretics bad for the kidney? Sean Bagshaw (Edmonton , Canada) Optimal use of ultrafiltration in fluid overload Amir Kazory (Gainesville, United States) Genomic medicine in the ICU: Ready for prime time? [Plenary lecture] Genomic medicine in the ICU: Ready for prime time? Andrew Shaw (Durham , United States) Genome wide associated studiesfor ICU patients [Plenary lecture] Genome wide associated studies in ICU patients Jean-Paul Mira (Paris , France) Diagnosis and management of sepsis in children [Plenary lecture] Diagnosis and management of sepsis in children Niranjan (Tex) Kissoon (Vancouver , Canada) Non-antibiotics approaches for treating severe infections [Plenary lecture] Non-antibiotic approaches for treating severe infections Jean Chastre (Paris , France) Ventilating the massively obese [Plenary lecture] Ventilating the massively obese patient John J Marini (St Paul , United States) Biomarkers should be included in the classification of renal dysfunction [Pro-con debate] Biomarkers should be included in the classification of renal dysfunction PRO : Michael Darmon (Saint-Priest-en-Jarez, France) CON : - Michael Joannidis (Innsbruck , Austria) Albumin is affordable [Pro-con debate] Albumin is affordable PRO : Albert Farrugia (Perth, Australia) CON : - Jukka Takala (Bern , Switzerland) Early tracheostomy [Pro-con debate] Early tracheostomy PRO : Marco Ranieri (Turin , Italy) CON : - Andres Esteban (Madrid , Spain) HES should not be used outside RCTs [Pro-con debate] HES should not be used outside RCTs PRO : Simon Finfer (Sydney , Australia) CON : - Monty G Mythen (London , United Kingdom) Colloids in sepsis [Pro-con debate] Colloids in sepsis PRO : Claude Martin (Marseille , France) CON : - Konrad Reinhart (Jena , Germany) Only large scale RCTs can tell what treatments work? [Pro-con debate] Only large scale RCTs can tell which treatments work? PRO : Simon Finfer (Sydney , Australia) - Derek C Angus (Pittsburgh , United States) CON : - John J Marini (St Paul , United States) Should we apply the SSC guidelines for hemodynamic resuscitation in septic shock? [Pro-con debate] Should we apply the SSC guidelines for hemodynamic resuscitation in septic shock? PRO : Mitchell Levy (Providence , United States) - Greg S Martin (Atlanta , United States) CON : - Jean-Louis Teboul (Le Kremlin-Bicêtre , France) ICU admission of cirrhotic patients is futile [Pro-con debate] ICU admission of cirrhotic patients is futile PRO : Pierre-François Laterre (Brussels , Belgium) CON : - Julia Wendon (London , United Kingdom) Do you measure CVP? [Pro-con debate] Do you measure CVP? PRO : Daniel De Backer (Brussels , Belgium) - Jean-Louis Teboul (Le Kremlin-
Bicêtre , France) CON : - Daniel Reuter (Hamburg , Germany) Blood lactate is a biomarker of hypoperfusion in sepsis [Pro-con debate] Blood lactate is a biomarker of hypoperfusion in sepsis PRO : Jan Bakker (Rotterdam , Netherlands) CON : - Rinaldo Bellomo (Melbourne, Australia) Is plateau pressure able to guide ventilation in ARDS? [Pro-con debate] Is plateau pressure able to guide ventilation in ARDS? PRO : John J Marini (St Paul , United States) CON : - Marco Ranieri (Turin , Italy) Still a place for the pulmonary artery catheter (RT) [Round table] Still a place for the pulmonary artery catheter Daniel De Backer (Brussels , Belgium) - Michael Pinsky (Pittsburgh , United States) - Jukka Takala (Bern , Switzerland) - Andrew Rhodes (London , United Kingdom) - Xavier Monnet (Le Kremlin-Bicêtre , France) - John Kellum (Pittsburgh , United States) Goal-directed perioperative optimization: My strategy (RT) [Round table] Moderators : Charles S Brudney (Durham , United States) Goal-directed perioperative optimization: My strategy Matthieu Biais (Bordeaux, France) - Simon Davies (York, United Kingdom) - Michael Sander (Berlin , Germany) - Andreas Hoeft (Bonn , Germany) - Daniel Reuter (Hamburg , Germany) Optimal amount of calories and proteins (RT) [Round table] Moderators : Adam Deane (Adelaide , Australia) Optimal amount of calories and proteins Michael Hiesmayr (Vienna , Austria) - Arthur Van Zanten (Ede , Netherlands) - Daren K Heyland (Kingston , Canada) - Jan Wernerman (Stockholm , Sweden) - Paul Wischmeyer (Aurora , United States) Big data in Critical Care [Round table] Big Data in Critical Care Jeremy M Kahn (Pittsburgh , United States) - Jean-Louis Vincent (Brussels , Belgium) - Theodore J Iwashyna (Ann Arbor, United States) - John C Marshall (Toronto , Canada) - Kenneth Christopher (Boston, United States) - Leo Anthony Celi (Cambridge, United States) - Djillali Annane (Garches , France) Balancing between syndromes and diseases (RT) [Round table] Balancing between syndromes and diseases Challenging diagnosis-based medicine (RT) [Round table] Challenging diagnosis-based medicine Ken Hillman (Liverpool , Australia) Should we abandon the concept of ARDS and sepsis [Round table] Should we abandon the concepts of ARDS and sepsis? Gordon Rubenfeld (Toronto , Canada) - Marco Ranieri (Turin , Italy) - Luciano Gattinoni (Milan , Italy) - Niall Ferguson (Toronto , Canada) - Clifford S Deutschman (Philadelphia , United States) - John C Marshall (Toronto , Canada) Microcirculation-targeted therapy: Are we ready? [Round table] Microcirculation-targeted therapy: Are we ready? Jan Bakker (Rotterdam , Netherlands) - Jacques Duranteau (Le Kremlin-Bicêtre , France) - Can Ince (Amsterdam , Netherlands) - Antonio Messias (Loures, Portugal) - Daniel De Backer (Brussels , Belgium) My tips and tricks for enteral nutrition (RT) [Round table] Moderators : Michael Hiesmayr (Vienna , Austria) My tips and tricks for enteral nutrition Stephen McClave (Louisville, United States) - Paul Wischmeyer (Aurora , United States) - Jean-Charles Preiser (Brussels , Belgium) - Jean Reignier (La Roche Sur Yon Cedex 9 , France) - Adam Deane (Adelaide , Australia) Statistics for dummies (TU) [Tutorial] Statistics for dummies Dominique Benoit (Ghent , Belgium) Management of severe ARDS (TU) [Tutorial] Management of severe ARDS Laurent Brochard (Toronto, Canada) Innate immunity (TU) [Tutorial] Innate immunity Thierry Calandra (Lausanne , Switzerland) Hematological emergencies (TU) [Tutorial] Hematological emergencies Michael Darmon (Saint-Priest-en-Jarez, France) ECMO (TU) [Tutorial] ECMO Alain Combes (Paris , France) Mechanical ventilation in ARDS (TU) [Tutorial] Mechanical ventilation in ARDS Dimitris Georgopoulos (Heraklion , Greece) Antimicrobial therapy of VAP (TU) [Tutorial] Antimicrobial therapy of VAP Jean Chastre (Paris , France) Necrotizing skin and soft tissue infections (TU) [Tutorial] Necrotizing skin and soft tissue infections Jan De Waele (Ghent , Belgium) Prevention of pulmonary postoperative complications (TU) [Tutorial] Prevention of pulmonary postoperative complications Samir Jaber (Montpellier , France) Plasmapheresis (TU) [Tutorial] Plasmapheresis Bertrand Guidet (Paris , France) Managing end-of-life care in the ICU (TU) [Tutorial] Managing end-of-life care in the ICU Ken Hillman (Liverpool , Australia) Ultrasound for intensivists (TU) [Tutorial] Ultrasound for intensivists Eric Maury (Paris , France) Nutritional support (TU) [Tutorial] Nutritional support Daren K Heyland (Kingston , Canada) Renal replacement therapies (TU) [Tutorial] Renal replacement therapies Ravindra Mehta (San Diego , United States) Medical management of abdominal hypertension (TU) [Tutorial] Medical management of abdominal hypertension Manu Malbrain (Antwerp , Belgium) Metabolic conundrums (TU) [Tutorial] Metabolic conundrums Mervyn Singer (London , United Kingdom) ICP management (TU) [Tutorial] ICP management Stephan A Mayer (New York , United States) Perioperative hemodynamic monitoring and optimization (TU) [Tutorial] Perioperative hemodynamic monitoring and optimization Mikhail Kirov (Arkhangelsk , Russia) How I use hemodynamic monitoring (TU) [Tutorial] How I use hemodynamic monitoring Azriel Perel (Tel Aviv , Israel) Interpretation of SvO2/ScvO2 (TU) [Tutorial] Interpretation of SvO2/ScvO2 Xavier Monnet (Le Kremlin-Bicêtre , France) Functional hemodynamic monitoring (TU) [Tutorial] Functional hemodynamic monitoring Michael Pinsky (Pittsburgh , United States) Extracorporeal lung support (TU) [Tutorial] Extracorporeal lung support Michael Quintel (Göttingen , Germany) Polytrauma (Tu) [Tutorial] Polytrauma Kjetil Sunde (Oslo , Norway) Subarachnoid hemorrhage (TU) [Tutorial] Subarachnoid hemorrhage Paul Vespa (Los Angeles , United States) Decompensated COPD (TU) [Tutorial] Decompensated COPD Tobias Welte (Hannover , Germany) Parenteral nutrition in the ICU (TU) [Tutorial] Parenteral nutrition in the ICU Paul Wischmeyer (Aurora , United States) Drugs of abuse (TU) [Tutorial] Drugs of abuse Janice L. Zimmerman (Houston , United States) Metabolic acidosis - an idiots guide (TU) [Tutorial] Metabolic acidosis: An idiots guide Monty G Mythen (London , United Kingdom) Acute myocardial infarction (TU) [Tutorial] Acute myocardial infarction Martin Möckel (Berlin, Germany) Protein metabolism (TU) [Tutorial] Protein metabolism Jan Wernerman (Stockholm , Sweden) Multidrug resistant bacteria (TU) [Tutorial] Multidrug resistant bacteria Robert Bonomo (Cleveland, United States) The various modes of mechanical ventilation (TU) [Tutorial] The various modes of mechanical ventilation Robert Chatburn (Cleveland, United States) Traumatic brain injury (TU) [Tutorial] Traumatic brain injury Giuseppe Citerio (Monza , Italy) Controversies in CPR (TU) [Tutorial] Controversies in CPR Jerry Nolan (Bath , United Kingdom) How I can use microcirculation to target therapy (W) [Workshop] How I can use the microcirculation to target therapy Jacques Duranteau (Le Kremlin-Bicêtre , France) - Jan Bakker (Rotterdam , Netherlands) - Can Ince (Amsterdam , Netherlands) - Didier Payen (Paris , France) - Daniel De Backer (Brussels , Belgium) My favoured future therapies in sepsis (W) [Workshop] My favoured future therapies in sepsis John C Marshall (Toronto , Canada) - Richard Hotchkiss (St Louis , United States) - Tom van der Poll (Amsterdam , Netherlands) - Didier Payen (Paris , France) - Steven Opal (Providence , United States)
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Skip to content past banner and navigation links Guidelines for the Diagnosis and Management of Asthma — Full Report Change Page The EPR-3 was initially posted to the NHLBI website in August 2007. Periodically edits are made to this document and these edits are logged onto this change page. As of August 5, 2008 the following edits have been made (specific wording changes