Clinical References for GlucoCrave Xtreme Diabetes, hypoglycemia and insulin-induced obesity are all epidemic conditions plaguing our society. In spite of years of medical research, these conditions, for the most part, go untreated effectively. Through the right combination of nutrients and herbal extracts, not only can we reduce the cravings for carbohydrate foods, but we can also lower insulin levels AND increase insulin-receptor site function. Through this three-way approach, glucose metabolism disorders can be effectively managed. Some of the many studies supporting this concept have been quoted as follows: “These data demonstrate that supplemental chromium had significant beneficial effects on glycosolated hemoglobin, glucose, insulin and cholesterol variables in subjects with type II diabetes.” Diabetes 1997: 46
“In conclusion, the efficacy and relative lack of toxicity of vanadyl derivatives (vanadium)… makes them a potential therapy in human diabetes in general and in insulin-resistant states in particular.” Molecular and Cellular Biochemistry. 1992: 109
“These results indicate that 3 weeks of treatment with vanadium improves hepatic and peripheral insulin sensitivity in insulin-resistant type II diabetes in humans.” Journal of Clinical Investigation 1995: 95
“A major advance in the use of vanadium as an insulin-mimetic has been the development of organic complexes which are 2 to 3 times as potent as inorganic vanatium… There is an emerging role for the use of vanadium in human diabetes.” Journal of the American College of Nutrition. 1998: 17 A partial list of other clinical studies used in the research for this formulation follow:
1. Lowenstein & Preger. Diabetes - New Look At An Old Problem. Harper & Row 2. West & Kalbfleisch. Influence of Nutritional factors on Prevalence of Diabetes. Diabetes. 1971;20: 99-108 3. Yudkin, J. Dietary Fat and dietary sugar in relation to ischemic heart-disease and diabetes. Lancet. 1964; 4-5 4. Durrington, PN. Is insulin atherogenic? Diabetic Medicine. 1992; 9: 597-600 5. Yudkin, J. Medical problems from modern diet. J Royal Coll of Physicians of London. 1975; 9(2): 161-164 6. Allred, JB. Too Much of A Good Thing? J Amer Dietetic Assoc. 1995; 95(4): 417-418
7. Cohen, MP, et al. High Prevalence of Diabetes in Young Adult Ethiopian Immigrants to Israel. Diabetes. 1988; 37: 824-828 8. Paolisso, G. et al. Pharmacologic Doses of Vitamin E Improve Insulin Action in Healthy Subjects and Non-insulin-dependent Diabetic Patients. Am J Clin Nutr. 1993; 57: 650-656 9. Urberg, M. And Zemel, MB. Evidence for Synergism Between Chromium and Nicotinic Acid in the Control of Glucose Tolerance in Elderly Humans. Metabolism.1987; 36(9): 896-899 10. Moan, A, et al. Mental Stress Increases Glucose Uptake During Hyperinsulinemia: Associations with Sympathetic and Cardiovascular Responsiveness. Metabolism. 1995; 44(10): 1303-1307 11. Nicholson, AL, and Yudkin, J. The Nutritional Value of the Low-Carbohydrate Diet Used in the Treatment of Obesity. Proc Nutr Soc. 1968; 28(1):13 A 12. Klurfeld, DM and Kritchevsky, D. The Western Diet: An Examination of its Relationship With Chronic Disease. J Am Coll Nutr. 1986; 5: 477-485 13. Mouratoff, GJ and Scott, EM. Diabetes Mellitus in Eskimos After a Decade. JAMA. 1973; 226(11): 1345-1346 14. O'Dea, K. Westernisation, Insulin Resistance and Diabetes in Australian Aborigines. Med J Aust. 1991; 155: 258-264 15. Yudkin, J. Evolutionary and Historical Changes in Dietary Carbohydrates. Am J Clin Nutr. 1967; 20(2): 108-115 16. Garg, A, et al. Effects of Varying Carbohydrate Content of Diet in Patients with Non-insulin-dependent Diabetes Mellitus. JAMA. 1994; 271(18): 1421-1428 17. Cahill, GF and Boston, MD. Physiology of Insulin in Man. Diabetes. 1971; 20(12): 785-799 18. Hollenbeck, CB and Coulston, AM. Effects of Dietary Carbohydrate and Fat Intake on Glucose and Lipoprotein Metabolism in Individuals with Diabetes Mellitus. Diabetes Care. 1991; 14: 744-785 19. Chen, YD, et al. Why do Low-fat High-carbohydrate Diets Accentuate Postprandial Lipemia in Patients with NIDDM? Diabetes Care.1995; 18(1): 10-16 20. Farquhar, JW, et al. Glucose Insulin and Triglyceride Responses to High and Low Carbohydrate Diets in Man. J Clin Invest. 1966; 45(10): 1648-1656 21. Zimmet, PZ. Hyperinsulinemia - How Innocent a Bystander. Diabetes Care. 1993;16(3): 56-70
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CULMINATING ACTIVITY: TRAVELING TO EXPONENTIA This culminating task addresses all standards in the unit and is designed to serve as an assessment task. Some parts of the items below are very explicit in order to assess student mastery of particular topics. However, in general, the questions do not give the same level of guidance as the learning tasks. In the learning tasks, students are g