Revision Date 07/12/2012Revision 2Supersedes date 07/12/2012 SAFETY DATA SHEET
1.1. Product identifier
1.2. Relevant identified uses of the substance or mixture and uses advised against
Processes involving incompatible materials. Processes that would lead to over-exposure of the operators.
1.3. Details of the supplier of the safety data sheet
Reagent Chemical Services18 Aston Fields RoadWhitehouse Industrial EstateRuncornCheshire WA7 3DLT: 01928 716903 (08.30 - 17.00)F: 01928 716425E: 1.4. Emergency telephone number
2.1. Classification of the substance or mixture
Physical and Chemical Hazards Met. Corr. 1 - H290Human health The Full Text for all R-Phrases and Hazard Statements are Displayed in Section 16.
Human healthWill cause severe burns. The product will cause serious burns to eyes which can result in blindness. Dusts or vapours will irritate the respiratory system with the possibility of causing burns dependent upon the extent of exposure and duration. Ingestion can result in serious internal damage and formation of scar tissue. Inhalation of vapour or mist may cause lung oedema.
EnvironmentDue to the alkalinity of the product it may produce a local pH change in water systems which can have a damaging effect on aquatic organisms. Discharge to soil may produce a local pH change which can have a damaging effect on crops and soil dwelling organisms.
Physical and Chemical HazardsVery corrosive to skin and eyes. Will corrode metal surfaces on sustained or repeated contact. May produce an exothermic reaction with acids.
2.2. Label elements
Label In Accordance With (EC) No. 1272/2008 SODIUM HYDROXIDE PEARL LRG
Causes severe skin burns and eye damage.
Wear protective gloves/protective clothing/eye protection/face protection.
IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Immediately call a POISON CENTER or doctor/physician.
Get medical advice/attention if you feel unwell.
Dispose of contents / container to hazardous waste depot.
Wash contaminated skin thoroughly after handling.
Specific treatment (see medical advice on this label).
IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
Wash contaminated clothing before reuse.
Absorb spillage to prevent material damage.
Store in corrosive resistant/… container with a resistant inner liner.
2.3. Other hazards
This product does not contain any PBT or vPvB substances.
3.1. Substances
4.1. Description of first aid measures
General informationCAUTION! First aid personnel must be aware of own risk during rescue! First aid personnel must protect themselves with all necessary personal protective equipment during the assistance of casualties. Always consider any dangers in the vicinity before approaching to treat the casualty. Check airway for any blockages. When breathing is difficult, properly trained personnel may assist the casualty by administering oxygen. If breathing has stopped perform CPR. Place unconscious person on the side in the recovery position and ensure breathing can take place. Never give anything by mouth to an unconscious person. If medical assistance is needed take as much detail as possible about the incident and hazardous materials involved with the casualty.
InhalationRemove victim immediately from source of exposure. Provide rest, warmth and fresh air. In case of severe exposure or if casualty feels unwell, obtain medical attention.
IngestionDo not induce vomiting. Rinse mouth thoroughly with water Get medical attention immediately!Skin contactRemove contaminated clothing and wash before re - use. Wash the skin with copious amounts of water. If clothing is difficult to remove or stuck to the skin then leave in place and flush affected area with water. Get medical attention immediately! SODIUM HYDROXIDE PEARL LRG
Eye contactMay cause permanent damage if eye is not immediately irrigated. Promptly wash eyes with plenty of water or eye wash solution while lifting the eyelids.If possible remove any contact lenses and continue to wash. Get medical attention immediately. Continue to rinse.
4.2. Most important symptoms and effects, both acute and delayed
General informationThe severity of the symptoms described will vary dependant of the concentration and the length of exposure.
Acute: Coughing. Irritation of the respiratory system. Delayed: Prolonged or repeated exposure to dusts may cause burns to the respiratory system with the possibility of lung edema.
IngestionAcute: Burns in the mouth, throat, stomach and gastrointestinal tract. Risk of perforation. Delayed: Scarring of the digestive system with possible blockages due to internal damage. Coma and death can occur following severe exposure.
Skin contactAcute: Chemical burns. Delayed: Scarring of the skin.
Eye contactAcute: Severe burns. Delayed: Permanent eye damage. Possible blindness.
4.3. Indication of any immediate medical attention and special treatment needed
Have eye wash facilities in place close to the operators' work area to provide immediate first aid prior to medical attention. All cases of exposure require immediate medical attention.
5.1. Extinguishing media
Extinguishing mediaThe product is non-combustible. Use fire-extinguishing media appropriate for surrounding materials. Small fires: Foam, carbon dioxide or dry powder. Large fires: Dry powder, foam or water spray/mist.
Unsuitable extinguishing mediaDo not use water jet as this can spread the fire. Do not use carbon dioxide in enclosed spaces with insufficient ventilation.
5.2. Special hazards arising from the substance or mixture
Hazardous combustion productsThe product is not combustible but may decompose in the event of a fire. Corrosive gases/vapours/fumes of: Sodium hydroxide. When the water component has evaporated there is a possibility that sodium oxides may be formed during fire.
Unusual Fire & Explosion HazardsContact with metals may form hydrogen gas which is flammable and can result in explosion. Containers of flammable liquids in the area of the fire can explode upon heating.
Specific hazardsCorrosive liquid. Sodium hydroxide mists or vapours will be formed.
5.3. Advice for firefighters
Special Fire Fighting ProceduresPrevent run-off from entering drains and watercourses. Be aware of dangers from other hazardous substances in the immediate area. Use water spray to cool unopened containers. Evacuate and keep non-emergency personnel away from the fire area until it is properly extinguished with no danger of re-ignition.
Protective equipment for fire-fightersSelf contained breathing apparatus and full protective clothing must be worn in case of fire.
6.1. Personal precautions, protective equipment and emergency procedures
Wear protective clothing as described in Section 8 of this safety data sheet. Avoid generation and spreading of dusts during clean up operations. Avoid ingestion of the product, inhalation of dusts and contact with skin and eyes when treating spillages. Restrict access to the area until the spillage is treated, if large amounts of vapours are produced that will be hazardous to others, evacuate the area. When any other effects of spillages will affect the safety of others the area should be evacuated.
6.2. Environmental precautions
Avoid unauthorised discharge to the environment. Do not discharge into drains, water courses or onto the ground. Large spillages or uncontrolled discharge to water systems must be alerted to the Environmental Agency or other regulatory body. If spillages to land cannot be treated safely or if contamination will occur the Environment Agency must be alerted immediately. If the substance has entered a foul drain or sewage system in significant quantity to cause a hazard the local Water Treatment Company must be informed. Clean up any spillages immediately, prevent material from spreading and entering drains or sewage systems.
6.3. Methods and material for containment and cleaning up
Fit drain covers where they are available if the spillage is likely to enter the drainage system. Dam around drains with sand or other compatible material. Carefully remove with scoop or shovel if safe to do so and transfer to waste containers. Avoid generation and spreading of dust. Collect spillage in containers, seal securely and deliver for disposal according to local regulations. Containers with collected spillage must be properly labelled with correct contents and hazard symbol. Flush area clean with lots of water. Be aware of potential for surfaces to become slippery. Ventilate area and allow to dry before allowing access.
6.4. Reference to other sections
Refer to sections 8 and 13 for additional information.
7.1. Precautions for safe handling
Avoid spilling, skin and eye contact. Avoid ingestion of the product. Avoid inhalation and spreading of dusts Do not eat, drink or smoke when handling. Do not mix with incompatible substances or mixtures. Ensure emergency procedures are in place to treat spillages and cope with other situations such as evacuation. Remove contaminated clothing/footwear/equipment before entering eating areas or other places that would expose others to the substance. Do not dispose of the substance to the environment through unauthorised means. Do not discharge to land or water including the drainage system. Wash at the end of each work shift, before eating, drinking, smoking and using the toilet. Do not use in areas close to drainage systems unless measures are in place to prevent access of product.
7.2. Conditions for safe storage, including any incompatibilities
Store in closed original container at temperatures between 15°C and 25°C. Store away from heat, direct sunlight and moisture. Store away from incompatible materials. It is advisable to store in a bunded area or use other protective measures such as a sump pallet or storage tray. Store in a stable situation to avoid spillages. Avoid freezing conditions. If the mixture is transferred to another container then this should be made of a compatible material. Consult with the packaging manufacturer about suitability. Do not store in containers made of aluminium or other light metals.
Storage ClassCorrosive storage.
7.3. Specific end use(s)
The identified uses for this product are detailed in Section 1.2.
Usage DescriptionUse product under conditions described in this datasheet. Avoid exposure of operators and others who may be affected by its use. Avoid overuse of the product which would create waste and potential spillages. Always use recommended personal protective equipment. Only use the product for its intended use in a safe manner, do not use for other purposes.
8.1. Control parameters
Biological Limit ValuesNo information availableNo information has been received from the manufacturers of the substance.
DNELIndustry Refers to sodium hydroxide as a substance.
No information available for PNEC of constituents.
8.2. Exposure controls
Engineering measuresProvide adequate ventilation, including appropriate local extraction, to ensure that the defined workplace exposure limit (WEL) is not exceeded. If vapours or mists are generated, work in a fume cupboard.
Respiratory equipmentUse suitable respiratory protection if vapours, mists or dusts are generated and there is insufficient ventilation or extraction. CAUTION: Air purifying respirators do not protect the user in oxygen deficient atmospheres, use air supplied system. When the concentration of atmospheric vapours is sufficient to cause skin irritation it is advisable to wear full face respiratory protection. Use respirator fitted with cartridge suitable for inorganic vapours including the substance of concern, type B is recommended. Respiratory protection should conform to the following standards. Consult with the supplier as to the compatibility of the equipment with the chemical of concern. BS EN 136: Full face masks. BS EN 140: Half-face masks. BS EN 143: Particulates. When a particulate respirator is used it is recommended to use at least Type P2, preferably P3. Powered air respirators should meet requirements of EN146 and EN12941. Airline fed respirators should meet the requirements of EN 270 and EN1835. Respiratory protection should be maintained in a proper condition and inspected at the frequency specified by current legislation.
Hand protectionUse full length gloves. Polyvinyl chloride (PVC). Viton rubber (fluor rubber). Butyl rubber. Nitrile. The most suitable glove must be chosen in consultation with the gloves supplier, who can inform about the breakthrough time of the glove material. For gloves involving total immersion 1.0mm thickness (if available) are recommended, at least 0.5mm and breakthrough time of >480 minutes. For splash resistance use minimum 0.5mm thickness and breakthrough time > 240 minutes. Gloves should have a breakthrough time sufficient for the amount of handling but allow dexterity for safe movement and handling. Gloves should conform to EN 374 (Chemical and Micro-organisms hazards). Be aware that the liquid may penetrate the gloves. Frequent change is advisable. When removing used gloves apply proper technique by avoiding skin contact with the outer surface. When packages of the product are being handled during storage or transport it is advisable to wear protective gloves to prevent damage to the skin.
Eye protectionWear approved chemical safety goggles conforming to EN 166.
Other ProtectionWear suitable protective clothing during transport, handling and storage operations connected with the product. Protective clothing should conform to the general requirements of EN 340:2003. Also consider EN 13034:2005; EN 14605:2005; EN 943:2002 dependent upon the situation resulting in exposure. Wear suitable protective footwear during handling of the product. When treating spillages it is recommended to wear protective boots, consult with the supplier as to the compatibility. Safety footwear should conform to standards EN 344 - 347. Wear plastic apron and full length gloves if handling large amounts. If there is a risk of splashing then wear a face shield. Have facilities in place to wash eyes in case of contact. If handling large amounts it is recommended to have a safety shower.
Hygiene measuresDo not eat, drink or smoke in the work area. Wash hands at the end of each work shift and before eating, smoking and using the toilet. Remove clothing when contamination will result in exposure to the substance, segregate and wash before re-use. Remove contaminated clothing when entering eating areas or other places that could lead to contamination of others with the product.
Environmental Exposure ControlsSee section 6 for details.
9.1. Information on basic physical and chemical properties
Vapour density (air=1)Not determined.
Vapour pressureNot determined.
Evaporation rateNot determined.
Evaporation FactorNot determined.
pH-Value, Conc. Solution ViscosityNot determined.
Solubility Value (G/100G Sodium hydroxide is very soluble in water.
Decomposition temperature (°C)Not determined.
Odour Threshold, LowerNot applicable.
Odour Threshold, UpperNot applicable.
Flash pointNot relevantAuto Ignition Temperature (°C)Not relevantFlammability Limit - Lower(%)Not relevant SODIUM HYDROXIDE PEARL LRG
Flammability Limit - Upper(%)Not relevant Partition Coefficient (N-Octanol/Water)Not determined.
Explosive propertiesThe mixture itself is not explosive but can produce hydrogen gas on reaction with metals which is explosive.
Explosive under influence of flame.
NoMore sensitive to shock than m-dinitrobenzene.
More sensitive to friction than m-dinitrobenzene.
Solid/Liquid Ignition On Contact With Air.
Solid: Burning time.
9.2. Other information
10.1. Reactivity
Exothermic and possible violent reaction with concentrated acids and organic halogen compounds. Possible exothermic reaction with dilute acid solutions. Flammable hydrogen gas is produced on reaction with light metals. Aluminium Zinc Tin and tin oxides.
10.2. Chemical stability
Air sensitive. Will form carbonates on reaction with atmospheric carbon dioxide. Stable when stored in sealed container at normal temperatures and in a suitable location.
10.3. Possibility of hazardous reactions
Hazardous reactions as specified in section 10.1. Heat and gaseous products may be formed that would build up pressure in a sealed container, do not mix with incompatible materials.
Hazardous PolymerisationWill not polymerise.
10.4. Conditions to avoid
Avoid heat, direct sunlight and moisture. Avoid contact with acids. Avoid storage in freezing conditions. Avoid storage with incompatible materials. Avoid exposure to the atmosphere, product is air sensitive. Avoid storage in an unstable manner or in a situation that would result in exposure to the product. Avoid storage near to unprotected drainage systems. It is advisable to store the product within some form of containment to prevent spillages reaching drainage systems.
10.5. Incompatible materials
Materials To AvoidAluminium, zinc, tin (formation of hydogen). Acids. Halogenated organic compounds If the substance is transferred to another container ensure compatibility. Consult with the packaging manufacturer on suitability of material.
10.6. Hazardous decomposition products
None under normal conditions. See section 5 for hazardous combustion products.
11.1. Information on toxicological effects
Toxicological informationInformation on toxicological properties has not been received from the manufacturer or supplier.
Acute Toxicity (Oral LD50)No information available.
No reliable information.
Acute Toxicity (Dermal LD50)No information available.
No reliable information.
Acute Toxicity (Inhalation LC50)No information available.
No reliable information.
Skin Corrosion/Irritation:Dose0.5ml of 5% w/v solution 2 hr RabbitPrimary dermal irritation index (PDI)4.33 after 1 hour to 3.1 after 7 days.
Erythema\eschar score2.6 at 24 hoursOedema score1.5 at 24 hoursTests on rabbits for up to 8 days showed the solution to be irritating. At or above 5% w/w sodium hydroxide is classed as corrosive to skin causing severe burns. OECD Guideline 404 (Acute Dermal Irritation / Corrosion)Corrosive to skin.
With a patch test using 1%, 2% and 4% solutions, the concentration found to produce mild to moderate irritation was 2%. Solutions as low as 0.5% can produce significant irritation.
Patch test for 48 hours showed sodium hydroxide to be irritating up to 2%. Above this concentration it is considered to be corrosive.
Serious eye damage/irritation:Below 2%w/w solutions are irritating. At or above 2% w/w they are corrosive. Tests on rabbits, OECD Guideline 405, Acute eye Irritation / Corrosion.
Respiratory or skin sensitisation:Respiratory sensitisationNo information available.
Skin sensitisationPatch Test: HumanNot Sensitising.
Germ cell mutagenicity:Genotoxicity - In VitroGene Mutation:No reliable information.
Despite information being unreliable the results from all tests were negative for genotoxicity.
Genotoxicity - In VivoChromosome aberration:Result obtained for micronucleus assay on mouse showed negative results. Chromosome aberration on grasshoppers showed some positive results.
Information is unreliable but the majority of test results are negative.
Carcinogenicity:CarcinogenicityScientifically unjustified.
Reproductive Toxicity:Reproductive Toxicity - FertilityNo information available.
No supplied or registered information.
Reproductive Toxicity - DevelopmentFetotoxicity: Dose Level: 2 microlitre doses of 0.001M NaOH Mouse SODIUM HYDROXIDE PEARL LRG
Unreliable information.
2 microlitre doses of 0.001 M sodium hydroxide produced mortality in approx. 46% of fetuses.
Specific target organ toxicity - single exposure:STOT - Single exposureNo information available.
Specific target organ toxicity - repeated exposure:STOT - Repeated exposureNo information available.
Unreliable information.
InhalationIrritation of the respiratory system. Coughing and difficulties in breathing. Headache. Burns to mucous membranes. May cause pulmonary edema, bronchitis or pneumonitis.
IngestionChemical burns to the mouth, oesophagus and stomach. Stomach pain and vomiting. May cause severe internal injury.
Skin contactCauses severe burns. Delayed effects may be scarring of the skin.
Eye contactStrongly corrosive. Causes severe burns. Immediate first aid is imperative. Risk of serious damage to eyes. Lacrimation. Delayed effects can be conjunctivitis, cataracts and glaucoma. Possible blindness.
EcotoxicityAlthough not classified as environmentally hazardous, harmful effects cannot be excluded in the event of improper handling or disposal. May cause a local alkaline pH shift in the aquatic environment. Do not allow to enter drinking water, waste water or soil.
12.1. Toxicity
Acute Fish ToxicityThe acute effects on fish are the damaging effect on fins due the increase in alkalinity. As pH increases above 9 the mortality rate increases. Outside the range of pH6.5 to 9.0 freshwater fish suffer adverse physiological effects increasing in severity until lethality is reached. Marine life suffers outside pH 6.5 to 8.5 due to the larger buffering capacity of salt water producing a more stable pH and a reduced tolerance to pH change.
Acute Toxicity - FishLC50 96 hours < 180 mg/l Cyprinus carpio (Common carp)This was a study on mortality. Unreliable information.
Acute Toxicity - Aquatic InvertebratesEC50 48 hours 40.4 mg/lSpecies: Ceriodaphnia sp. ImmobilityAcute Toxicity - Aquatic PlantsScientifically unjustified.
Acute Toxicity - MicroorganismsNot available.
Unreliable information.
Chronic Toxicity - Fish Early life StageNot available.
The registered information is unreliable. Semi-static, freshwater tests on guppies showed adverse effects on survival rate and growth. 25 to 100 mg/l produced significant changes in the biology of the fish.
Short Term Toxicity - Embryo and Sac Fry StagesNot available.
Chronic Toxicity - Aquatic InvertebratesScientifically unjustified.
Acute Toxicity - TerrestrialNot available.
No supplied or registered informationToxicity to soil:No registered or supplied information.
Toxicity to terrestrial plants:No registered or supplied information.
12.2. Persistence and degradability
PhototransformationNot relevantStability (Hydrolysis)Scientifically unjustified.
When dissolved in water, sodium hydroxide dissociates to form hydroxide ions. This dissociation is reduced as the pH inreases.
BiodegradationScientifically unjustified.
Biological Oxygen DemandNo information available.
No supplied or registered informationChemical Oxygen DemandNo information available.
No supplied or registered information 12.3. Bioaccumulative potential
Bioaccumulative potentialScientifically unjustified. Due to its high water solubility, sodium hydroxide is not expected to bioaccumulate. It is an inorganic compound.
Bioaccumulation factorNot relevantPartition coefficientNot determined.
12.4. Mobility in soil
Mobility:Sodium hydroxide is present in the environment as sodium and hydroxyl ions. The product is miscible with water and will spread in water systems. It will be absorbed into soil with the possibility of travelling into groundwater when large or continuous discharges occur. Sodium hydroxide solutions will penetrate further into the soil as dilution increases. Some ion exchange will occur, sodium will become part of the naturally occuring sodium in the environment. There is the possibility that some hydroxide will remain in solution and travel towards groundwater.
Adsorption/Desorption CoefficientScientifically unjustified.
Henry's Law ConstantNot available.
No supplied or registered informationSurface tensionNot available.
No supplied or registered information 12.5. Results of PBT and vPvB assessment
This product does not contain any PBT or vPvB substances.
12.6. Other adverse effects
May create a local pH change in soil which can have a damaging effect on crops. Discharge into a foul drain can be a hazard to operators working on the system. Will affect drinking water supplies.
General informationAny waste material is classed as hazardous waste, it should only be disposed of through licenced waste handlers and treatment sites. Do not allow unauthorised disposal to the environment. If operators are exposed to vapours during the disposal process then suitable respiratory protection should be worn. All other personal protective equipment as described in section 8 should be worn.
13.1. Waste treatment methods
Dispose of waste and residues in accordance with local authority requirements. Avoid unauthorised disposal. Do not dump illegally onto land or into water. Uncleaned empty containers should be treated as hazardous waste. Waste material should not be disposed of directly to drain. Neutralisation is recommended before disposal, this should be carried out by a reputable waste disposal company. IF WASTE IS NEUTRALISED ON SITE BE AWARE THAT A VIGOROUS AND EXOTHERMIC REACTION MAY OCCUR. When dealing with waste always consider the waste management hierarchy of Prevention, Preparation for re-use, Recycling, Recovery and Disposal. It is advisable to minimise waste at source if possible, then re-use, recover or recycle wherever possible before considering waste disposal options.
14.1. UN number
14.2. UN proper shipping name
14.3. Transport hazard class(es)
14.4. Packing group
14.5. Environmental hazards
Environmentally Hazardous Substance/Marine PollutantNo.
14.6. Special precautions for user
14.7. Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code
15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture
Statutory InstrumentsThe Chemicals (Hazard Information and Packaging for Supply) Regulations 2009 (S.I 2009 No. 716). Control of Substances Hazardous to Health.
Guidance NotesWorkplace Exposure Limits EH40. Approved Classification and Labelling Guide (CHIP 4) ECHA Guidance on the Compilation of Safety Data Sheets, September 2011.
EU LegislationRegulation (EC) No 1907/2006 of the European Parliament and of the Council of 18 December 2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH), establishing a European Chemicals Agency, amending Directive 1999/45/EC and repealing Council Regulation (EEC) No 793/93 and Commission Regulation (EC) No 1488/94 as well as Council Directive 76/769/EEC and Commission Directives 91/155/EEC, 93/67/EEC, 93/105/EC and 2000/21/EC, including amendments. Regulation (EC) No 1272/2008 of the European Parliament and of the Council of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006 with amendments. Regulation (EU) 453/2010.
15.2. Chemical Safety Assessment
Information from the manufacturer of the raw material has not been received regarding Chemical Safety Assessments, Exposure Scenarios or a Chemical Safety Report.
General informationUnder REACH Material Safety Datasheets (MSDS) are referred to as Safety Datasheets (SDS). This datasheet is not intended to be a replacement for a full risk assessment, these should always be carried out by competent persons.
Information SourcesRaw material safety data sheets. ECHA website.
Revision CommentsChange to section 14Revision Date Causes severe skin burns and eye damage.


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