Qi-Mood™ NUTRITIONALLY SUPPLIES THE IMMEDIATE METABOLIC PRECURSOR TO SEROTONIN
Dietary supplementation may enhance levels of:
-May reduce discomfort in patients with chronic pain
-May regulate feeding patterns and have positive bariatric (weight management) effects
5-Hydroxytryptophan (5-HTP) is the immediate precursor in the biosynthesis of the
neurotransmitter 5-hydroxytryptamine ( 5 HT or serotonin). 5-HT is synthesized from the amino acid L-tryptophan. 5-HTP has replaced the use of L-tryptophan in the United States. In 1989 patients taking L-tryptophan developed a negative and debilitating reaction called eosinophilia-myalgia syndrome. Upon further study it was determined that the culprit was not the L-tryptophan. It was actually a bacterial contaminant in the formula. L-tryptophan products associated with the syndrome were found to come from genetically modified bacterial recombinant production methods. Even though L- tryptophan was proven to be safe
it never recovered from this incident. 5-HTP was created to fill the gap created by the removal of L-tryptophan in the marketplace.
Small amounts of 5-HTP, as well as serotonin, are found in: bananas, tomatoes, plums, avocados, eggplant, walnuts and pineapples. A common commercial source of 5-HTP is Griffonia simplicifolia, a relative to carob. 5-HTP’s possible pain reduction benefit comes from its conversion to serotonin and to the observed effect of raising beta-endorphin and platelet met-enkephalin levels. Serum leptin levels increased following 5-HTP injection in mice. This may explain 5-HTP’s beneficial effect on weight management. Additionally, 5-HTP has been shown to reduce carbohydrate intake. Qi-Mood™
Patients on MAOIs (approved 2 weeks after discontinuation)
Should not be used concurrently with medications such as: SSRIs, tricyclic
Should not be used concurrently with serotonin 5-HT1 receptor agonists
Including Naratriptan, Sumatriptan, and Zolmitriptan.
Patients with ischemic heart disease (Hx of myocardial infarction, angina
Patients with Hx of coronary artery spasm
Side effects: Due to excessive serotonin production side effects could include: Nausea, diarrhea, loss of appetite, vomiting, difficult breathing, dilation of pupils, exaggerated reflexes, loss of muscle coordination, blurring of vision and cardiac dysrhythmias. Note:
Carbidopa may increase 5-HTP transport across the blood brain barrier due to decreased peripheral 5-HTP metabolism. Methyldopa inhibits conversion of 5-HTP to serotonin. Qi-Mood™ Serving Size 1 veggie capsule Servings Per Container 120
SUGGESTED DOSE: As a dietary supplement, take 1-2 capsules twice daily between meals or as directed by your healthcare professional.
REFERENCES: 1. PDR for Nutritional Supplements, 1st Ed. Medical Economics/Thomson Healthcare. 2001. 2. Byerley WF, Judd LL, Reimherr FW, et al. 5-Hydroxy-tryptophan: a review of its antidepressant efficacy and adverse effects. J Clin Psychopharmacol.1987; 7:127-137. 3. Cangiano C, Ceci F, Cascino A, et al. Eating behavior and adherance to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan. Am J Clin Nutr. 1992; 56:863-867. 4. Caruso I, Sarzi Puttini P, Cazzola M, Azzolini V. Double-blind study of 5-hydroxytryptophan
versus placebo in the treatment of primary fibromyalgia syndrome. J Int med Res. 1990; 18:201-209. 5. Ceci F, Cangiano C, Cairella M, et al. The effects of oral 5-hydroxytryptophan administration on feeding behavior in obese adult female subjects. J Neural Transm. 1989; 76:109-117. 6. Genazzani AR, Sandrini G Facchinetti F, et al. Effects of L-5HTP with and without carbidopa on plasma beta-endorphin and pain perception. Possible implications in migraine prophylaxis. Cephalgia.1986; 6:241-245. 7. Ribeiro CA. L-5-Hydroxytryptophan in the prophylaxis of chronic tension-type headache: a
double-blind, randomized, placebo-controlled study. For the Portuguese Head Study. Headache. 2000;40:451-456. 8. Yamada J, Ujikawa M, Sugimoto Y. Serum leptin levels after central and systemic injection of a serotonin precursor, 5-hydroxytryptophan, in mice.
Wilderness and Remote First Aid Pre-Course Suggested Self-Study Material The American Red Cross Wilderness and Remote First Aid class is a hybrid course that builds on skills and knowledge offered in basic community level First Aid classes along with an introduction to some of the more advanced techniques presented in programs like BSA Lifeguard, American Red Cross Lifeguarding and Fir