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Bio-Beads SM adsorbents are neutral, macroporous polymeric Bio-Beads SM-2 nonpolar polystyrene adsorbents are particu- beads of high surface area for adsorbing organics from aqueous larly useful for the adsorption of nonpolar substances or sur- solutions. Each bead is composed of a large number of highly face active agents from aqueous solutions.
crosslinked microspheres, giving it high surface area and The following reference cite the use of Bio-Beads SM-2 adsor- uniform pores. Bio-Beads adsorbents can be used with a variety bents for the analysis of organic compounds, drugs, biologicals, of solvents, including alcohols, petroleum ether, diethyl ether, foods, pesticides, chemicals, metals, and detergents. For more hexane, and solvent mixtures, as well as with aqueous media.
information on Bio-Beads SM adsorbents, request the They have excellent physical stability and withstand Applications for Bio-Beads SM-2
Trace organics
Wigilius, B., Boren, H., Cvarlberg, G. E., Retention and
Rotsch, T. D., Sydor, R. J. and Pietrzyk, D. Grimvall, A., Lundgren, B. V. and Savenhed, sorption of sulfas J., J. Chrom. Sci., 17, 339-344 (1979).
R., J. Chromatog., 391, 169-182 (1987).
Separation of
Junk, G.A., Richard, J. J., Grieser, M. D., cannabinoids
Witiak, D., Witiak, J. L., Arguello, M. D., from cannabis
J. Chromatog., B205, 444-450 (1981).
Vick, R., Svec, H. J., Fritz, J. S. and Calder, G. V., J. Chromatogr., 99, 745-762 (1974).
Robinson, J. L., Marshall, M. A., Draganjac, of benzo[a]
M. E. amd Noggle, L. C., Anal. Chim. Acta, J.Chromatogr., 193, 197-206 (1980).
pyrene in
115, 229-238 (1980).
cigarette smoke
Moore, R.A. and Karasek, F. W., Inter. J. condensate
Environ. Anal. Chem., 17, 187-202 (1984).
Digregorio, G.J., J. Chromatogr., 101,
Osterroht, C., J. Chromatogr., 101, 289-298
antagonists in
human urine
Picer, N. and Picer, M., J. Chromatogr., Drugs in urine
Roerig, D. L., Lewand, D., Mueller, M. and hydrocarbons 193, 357-369 (1980).
Wang, R. I. H., J. Chromatogr., 110,
Separation of
Grieser, M.D. and Pietrzyk, D. J., Anal. Bastos, M. L., Jukofsly, D. and Mule, S. J., nitro- and
Chem., 45, 1348-1353 (1973).
J. Chromatogr., 81, 93 (1973).
Morphine and
Ulrich, L. and Ruegsegger, P., Arch. Toxicol., Chu, C. and Pietrzyk, D. J., Anal. Chem., codeine in urine 45, 241-248 (1980). German.
46 (3), 330-340 (1974).
Morphine in
Clinical Chem., 20 (2), 177-183 (1974).
Hux, R. A., Mohammed, H. Y. and Cantwell, in blood plasma F. F., Anal. Chem., 54, 113-117 (1982).
Drugs in blood
Z. Rechtsmedizin, 81, 25-30 (1978).
Anal. Biochem., 90, 119-125 (1978).
Pharmaceutical Mohammed, H. Y. and Cantwell, F. F.,
Salari, H., J. Chromatogr., 419, 103-111
drug syrups
Anal. Chem., 50 (3), 491-496 (1978).
from plasma
Extraction of
drugs from
M. L., J. Chromatrogr., 108, 107-116
Delaborde, S., Loosli, H. R., Ponelle, M., Griesser, R. amd Maurer, G., J. High stomach fluid
Resolution Chromatography & Chromatography
, 10, 71-76 (1987).
Polar and
Dieterle, W., Faigle, J. W. and Mory, H., non-polar drug
J. Chromatogr., 168, 27-34 (1979).
of resin with
Orvidas, M. C., J. Chromatogr., 378, 9-16
benzyl bromide
microbial fatty
acid analysis

Purification of
Landt, M., Boltz, S. C. amd Butler, L. G., aminobenzyl-
Biochem., 17 (5), 915-919 (1978).
Plant hormones Stafford, A. E., Kunhle, J. A., Corse, J. and
Hautala, E., J. Chromatogr., 294, 485-488
Free rhodamine Spack, E. G., Jr., Packard, B., Wier, M. L.
Funke. P.T., Ivashkiv. E., Malley. M.F. and and Edidin, M., Anal. Biochem., 158,
(derivatized in
Cohen, A.I., Anal. Chem., 52, 1086–1089,
Crude plasma
Tamura, M., Harris, T. M. Higashimori, K., clean-up
Sweetman, B. J., Blair, I. A. and Inagami, T., Biochem., 26, 2797-2806 (1987).
Flavonoids from Rosler, K. H. and Goodwin, R. S., J. Natural
Salari, H. and Steffenrud, S., J. Chromatogr., Products, 47 (1), 188 (1983).
from plasma
378, 35-44 (1986).
Acid dyes
Hamberg, M., Anal. Biochem., 55, 368-378
J. Chromatogr., 172, 327-334 (1979).
Naringin and
Chandler, B. V. and Johnson, R.l., Proc. Int. Prostaglandins
limonin from
Soc. Citriculture, 2, 885-888 (1981).
adsorption from Wakelyn, C. E., Prostaglandins, 21,
grapefruit juice
biological fluid
Triadimefon in
Nickless, G. and Spitzer, T., J. Chromatogr., Isolation of
Stafford, T. W., Duhamel, R. C., Haynes, C. grape wine
208, 409-413 (1981).
proline and
V. and Brendel, K., Life Sciences, 31,
proline from
fossil bone
Anabolic steroids Verbeke, R., J. Chromatogr., 177, 69-84
Indium treated
in animal tissue (1979).
adsorbent to
Anal. Chim. Acta, 200, 171-179 (1987).
and urine
humic complexes

Steroids from
Shacklleton, C. H. L., Sjovall, J. and Wisen, O., Clin. Chim. Acta, 27, 354-356 (1970).
Gomez-Bellnchon, J. I., Grimalt, J. O. and Albaiges, J., Environ. Sci. Technol., 22,
Extraction of
Bradlow, H. L., Steroids, 11, 265 (1968).
fatty acids in
sea water
Bile acids
Bulletin of Chemical Society of Japan, 52 (1),
Walton, H. F., Anal. Chem., 49 (14),
from water
Bile acids
Schwartz, H. P., v. Bergmann, K. and
Paumgartner, G., Clinica Chimica Acta, 50,
197-206 (1974).
Levesque, D. and Mallet, V. N., Intern. J. Triton X-100
Holloway, P. W., Anal. Chem., 53, 304-308
Environ. Anal. Chem., 16, 139-147 (1983).
from water
Drexler, G., Eichinger, A., Wolf, C. and Carbamate
Sundaram, K. M. S., Szeto, S. Y. and Hindle, Seighart, W., J. Immun. Methods, 95,
R., J. Chromatogr., 177, 29-34 (1979).
McNeil, E. E. and Otsen, R., J. Chromatogr., pesticides
132, 277-286 (1977).
Anal. Biochem., 142, 226-231 (1984).
Ethyl and
Paschal, D. D., Bicknell, R. and Dresbach, D., Welling, G. W., et. al., J. Chromatogr., 297,
Anal. Chem., 49, (11) 1551-1554 (1977).
Metsikko, K., van Meer, G. and Simons, K., Fenitrothion
Volpe, G. and Mallet, V. N., Chromatographia, The EMBO Journal, 5 (13), 3429-3435
14 (6), 333-336 (1981).

Bonomo, E. A. and Swaney, J. B., J. Lipid detergent
Research, 29, 380-384 (1988).
LeBel, G. L., Williams, D. T., Griffith, G. and Benoit, F. M., J. Assoc. Off. Anal. Chem., 62,
Anal. Biochem., 164, 331-335 (1987).
Anal. Biochem., 130, 393-396 (1983).
Carboxylic acid Jahanginr, JL. M. and Samuelson, O.,
Lorusso, D. J. and Green, F. A., Science, 188,
from aqueous
J. Chromatogr., 237, 371-379 (1982).
Shechter, I. and Bloch, K., J. Biol. Chem., 246
Hasanain, M. A. and Hines, A. L., Ind. Eng. Chem. Process Des. Dev., 20, 621-625
NP-40 detergent Momoi, T., Biochem. Biophys. Res. Commun.,
87, 541-549 (1979).
Use in HPLC
Baum, R. G., Saetre, R. and Cantwell, F. F., column as
Anal. Chem., 52 (1), 15-19 (1980).
Emulgen 911
Gibson, G. G., and Schenkman, F. B., J. Biol. ground material
Chem., 253, 5957-5963 (1978).
Benzenesulfonic Rotsch, T. D. and Pietryzk, D. J.,
Warner, M., J. Biol. Chem., 257 (21), 12995-
Anal.Chem., 52 (8),, 1323-1327 (1980).
Use in TLC
Pietryzk, D. J. Ritsch, T. D. and Leuthauser, Emulphogene
Brunch, R. C., Thotakura, N. R. and Bahl, O. P., as stationary
S. W., J. Chromatogr. Sci., 17, 555-561
J. Biol. Chem., 261 (20), 9450-9460 (1986).
Drexler, G., Eichinger, A., Wolf, C. and microtiter
Sieghart, W., J. Immunological Methods, 95,
plates with
detergent soluble
Metal cation
Mackey, D. J., J. Chromatogr., 242, 275-287
Metal ion
adsorption using Staskiewicz, M., Talanta, 35 (1), 65-67
loaded adsorbent
Green, L. W., Elliot, N. L. and Longhurst, T. impregnation
H., Anal. Chem., 55, 2394-2398 (1983).
with TBP for
actinides from
fission products


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