SAFETY DATA SHEET SECTION 1: Identification of the substance/mixture and of the company/undertaking Product identifiers Product name
: A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
Relevant identified uses of the substance or mixture and uses advised against
: Laboratory chemicals, Manufacture of substances
Details of the supplier of the safety data sheet SECTION 2: Hazards identification Classification of the substance or mixture
Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008. This substance is not classified as dangerous according to Directive 67/548/EEC.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Other hazards - none SECTION 3: Composition/information on ingredients Substances Synonyms
No components need to be disclosed according to the applicable regulations.
SECTION 4: First aid measures Description of first aid measures If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. In case of skin contact Wash off with soap and plenty of water. In case of eye contact Flush eyes with water as a precaution. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 Indication of any immediate medical attention and special treatment needed no data available
SECTION 5: Firefighting measures Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Special hazards arising from the substance or mixture Carbon oxides, nitrogen oxides (NOx) Advice for firefighters Wear self contained breathing apparatus for fire fighting if necessary. Further information no data available
SECTION 6: Accidental release measures Personal precautions, protective equipment and emergency procedures Avoid dust formation. Avoid breathing vapors, mist or gas. For personal protection see section 8. Environmental precautions Do not let product enter drains. Methods and materials for containment and cleaning up Sweep up and shovel. Keep in suitable, closed containers for disposal. Reference to other sections For disposal see section 13. SECTION 7: Handling and storage Precautions for safe handling Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire protection. For precautions see section 2.2. Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Specific end use(s) A part from the uses mentioned in section 1.2 no other specific uses are stipulated
SECTION 8: Exposure controls/personal protection Control parameters Components with workplace control parameters Exposure controls Appropriate engineering controls General industrial hygiene practice. Personal protective equipment Eye/face protection Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Body Protection Choose body protection in relation to its type, to the concentration and amount of dangerous substances, and to the specific work-place., The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Respiratory protection is not required. Where protection from nuisance levels of dusts are desired, use type N95 (US) or type P1 (EN 143) dust masks. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Control of environmental exposure Do not let product enter drains.
SECTION 9: Physical and chemical properties Information on basic physical and chemical properties
Flammability (solid, gas) no data available
Other safety information no data available SECTION 10: Stability and reactivity 10.1 Reactivity 10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions 10.4 Conditions to avoid 10.5 Incompatible materials 10.6 Hazardous decomposition products
Other decomposition products - no data available In the event of fire: see section 5
SECTION 11: Toxicological information 11.1 Information on toxicological effects Acute toxicity no data available Skin corrosion/irritation no data available Serious eye damage/eye irritation no data available Respiratory or skin sensitization no data available Germ cell mutagenicity no data available
No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity no data available Specific target organ toxicity - single exposure no data available Specific target organ toxicity - repeated exposure no data available Aspiration hazard no data available Additional Information RTECS: TW3590600
Lowered blood pressure, To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
SECTION 12: Ecological information 12.1 Toxicity 12.2 Persistence and degradability 12.3 Bioaccumulative potential 12.4 Mobility in soil 12.5 Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
12.6 Other adverse effects SECTION 13: Disposal considerations 13.1 Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Contaminated packaging Dispose of as unused product. SECTION 14: Transport information 14.1 UN number 14.2 UN proper shipping name 14.3 Transport hazard class(es) 14.4 Packaging group 14.5 Environmental hazards 14.6 Special precautions for user
SECTION 15: Regulatory information
This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006.
15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture 15.2 Chemical Safety Assessment
For this product a chemical safety assessment was not carried out
SECTION 16: Other information
Sigma - E9658
Agomelatine (pron. Ag-o-mella-teen) What is agomelatine used for? Agomelatine (also known by its trade name Valdoxan®) is used to help treat the symptoms of depression. It is made as tablets. What is the usual dose of agomelatine? The usual dose of agomelatine is 25mg once day at bedtime, although some people need 50mg a day. How should I take agomelatine? Swallow the tablets with