Microsoft word - beyond mammograms _oct 08 newsletter_.doc
Beyond Mammograms & Tamoxifen: 2 Cheap Tips to Help Decrease Your Breast Cancer Risk by over 50 to 67%! Copyright 2008, Douglas Husbands, DC, CCN, ABAAHP Athens Chiropractic Clinic 951 Industrial Rd., Suite B San Carlos, CA 94070 (650) – 593 – 4447 www.drhusbands.com
According to researchers from UC San Diego, Harvard University, Rutgers University
and other research facilities, 1760 females who had vitamin D blood levels of at least 52
ng/ml, had at least a 50% decreased incidence of breast cancer1. Blood levels of 52 ng/ml
of vitamin D correspond to 4000 IU intake per day. A simple, relatively inexpensive
blood test can measure your blood vitamin D levels. We provide this test through our
office in coordination with a local laboratory. According to current research studies2 3 4, Indole 3 Carbinol (I3C) and a metabolite of
I3C called Di-indolyl-methane (DIM), significantly increase the anti-cancer estrogen
metabolite, 2-hydroxyestrone, and greatly lower the cancer promoting estrogen
metabolite, 16-alpha-hydroxyestrone. A simple, special urine test can measure the 2 and
16 hydroxyestrone levels5. We provide these special urine tests kits through our office. So come in to pick up the forms and kits to check your vitamin D levels and your 2 and
16 hydroxyestrone levels to see where you are at regarding your breast cancer risk. If
necessary, 2 cheap supplements alone can help decrease your breast cancer risk by 50 to
“What are These 2 Things You Refer To?”
What are these and what dose gives these results? Get 4000 IU of Vitamin D3 and 200 to
400 mg of DIM or Indole 3 Carbinol each day! That’s it! According to research, these
nutrients can significantly help decrease your risk for breast cancer. But the key is
getting an effective, highly absorbable form of each of these supplements so you get an
“You’re making a Bold Statement! Is There Precedent for Such a Statement?”
Yes that’s a bold statement, but there are precedents for some simple nutrients having a
major preventive effect on decreased risk for disease. Take for example the story behind
the discovery of adequate levels of the B-vitamin folic acid significantly decreasing the
risk of neural tube defects in newborns (i.e. spina bifida, and a major part of the brain not
developing in the womb called anacephaly) from the late 1960’s and early 1970’s.
The story begins with Dr. Kilmer McCulley’s research in the 1960’s looking at the
relationship between B-vitamins, including folic acid and a potentially harmful blood
metabolite called homocysteine. (Note: Elevated homocysteine is now verified to be a
major risk factor for cardiovascular damage6, Alzheimer’s7, depression, PCOS, and
various types of cancer including breast cancer8) Dr. McCulley was ridiculed and lost his
research funding and his job proposing that these vitamins could change blood
homocysteine. Subsequently in 1968, Dr. Smithells research was published proposing
that folic acid could prevent spina bifida and other major neural tube birth defects9. He
was ridiculed by conventional medicine. Smithells published additional research in 1980
showing a stronger association between folic acid and prevention of neural tube defects10.
His findings were still resisted by conventional medicine and were still not implemented
as standard care for pre-pregnancy recommendations. By 1993, Oakley published
research saying that not only did folic acid greatly decrease the risk of babies having
spina bifida, but also greatly decreasing the risk of babies being born without a brain11!
That finally got the attention of conventional medicine and now it would be considered
malpractice for any doctor to fail to recommend adequate folic acid and B-vitamins to
“So what is I3C or DIM, and How Does It Help Decrease Breast Cancer Risk?”
I3C is a compound found in veggies like broccoli, cauliflower, cabbage and Brussels
sprouts. DIM is a more stable form of I3C. Both have been shown to raise the “good” 2-
hydrocystrones and lower the “bad” 16-alpha-hydroxyestrones12. As previously
mentioned, the 2-hydroxyestrones are implicated with decreased breast cancer risk, and
the 16-alpha-hydroxyestrones with increased breast cancer risk. For a more detailed
explanation of how this occurs in your body, you can read my articles from the January
and February 2007 issues of my newsletter in the “newsletter archives” section of our
“So how can I Get Started on Helping to Decrease my Breast Cancer Risk by at Least 50 to 67%?”
Through our office, we offer both the testing of Vitamin D and the urine test for the 2 and
16 hydroxyestrones. We also use effective, highly absorbable forms of vitamin D, I3C
and DIM that have shown to bring the blood vitamin D levels and the urinary 2 and 16
hydroxyestrones to levels which scientific research studies have indicated helping
provide at least a 50-67% decreased risk of breast cancer. We can provide you with this
limited service for this specific purpose at a very affordable cost. Contact Dr. Husbands
at www.drhusbands.com or by calling 650-593-4447. References:
1 Garland C, Gorham E, Mohr S, et. al. Vitamin D and prevention of breast cancer: Pooled analysis. J
Steroid Biochem Mol Biol. 2007;103:708-11.
2 Gruber C, et. al., Production and Actions of Estrogens. NEJM 2002;346:340-50.
3 Telang N, Katdare M, Bradlow H, et. al. Inhibition of proliferation and modulation of estradiol
metabolism: novel mechanisms for breast cancer prevention by the phytochemical indole-3-carbinol Proc
4 Meng Q, Goldberg I, Rosen E, et. al. Inhibitory effects of indole-3-carbinol on invasion and migration in
human breast cancer cells. Breast Cancer Res Treat 2000;63:147-52.
5 Ursin G, London S, Stanczyk F, et. al. A pilot study of urinary estrogen metabolites (16 -OHE1 and 2-
OHE1) in postmenopausal women with and without breast cancer. Environmental Health Perspectives.
6 Stone D, McCarron P, Smith G. Similarities in the epidemiology of neural tube defects and coronary
heart disease: is homocysteine the missing link? J Epidemiol Community Health. 1999;53:789-93
7 Seshadri S, Beiser A, Selhub J, et. al. Plasma homocysteine as a risk factor for dementia and alzheimer's
8 Zhang S, Willett W, Selhub J, et. al. Plasma folate, vitamin B6, vitamin B12, homocysteine, and risk of
breast cancer. J Natl Cancer Inst. 2003;95:373-80.
9 Smithells R, D’Arcy E, McAllister E. Dev. Med. Child Neurol (Suppl.). 1968;15:6-10.
10 Smithells R, Shepard S, Schorah C, et al. Possible prevention of neural-tube defects by periconceptional
vitamin supplementation. Lancet 1980:339;340.
11 Oakley G. Folic acid-preventable spina bifida and anencephaly. JAMA 1993;269:1292-3.
12 Wong G, Bradlow L, Sepkovic D, et. al. Dose-ranging study of indole-3-carbinol for breast cancer
prevention. J Cell Biochem Suppl 1997;S28-29:111-16.
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